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ChemicalBook >> CAS DataBase List >>2-(5-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-N-(2-methoxyphenyl)butanamide

2-(5-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-N-(2-methoxyphenyl)butanamide

2-(5-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-N-(2-methoxyphenyl)butanamide Structure
2-(5-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-N-(2-methoxyphenyl)butanamide structure
CAS No.
522650-83-5
Chemical Name:
2-(5-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-N-(2-methoxyphenyl)butanamide
Synonyms
CS-2302;SW-044248;SW-044248, >98%;SW 044248;SW044248;SW044248 >=98% (HPLC);SW 044248,Topoisomerase,inhibit,SW-044248,SW044248,Inhibitor;2-(5-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-N-(2-methoxyphenyl)butanamide;Butanamide, 2-[(5-ethyl-5H-1,2,4-triazino[5,6-b]indol-3-yl)thio]-N-(2-methoxyphenyl)-;
2-(5-Ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfanyl)-N-(2-methoxy-phenyl )-butyramide
CBNumber:
CB83059120
Molecular Formula:
C22H23N5O2S
Molecular Weight:
421.52
MDL Number:
MFCD03487851
MOL File:
522650-83-5.mol
MSDS File:
SDS
Last updated:2023-09-04 16:42:00
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2-(5-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-N-(2-methoxyphenyl)butanamide Properties

storage temp. 2-8°C
solubility DMSO:10.5(Max Conc. mg/mL);24.91(Max Conc. mM)
DMF:5.0(Max Conc. mg/mL);11.86(Max Conc. mM)
Ethanol:1.0(Max Conc. mg/mL);2.37(Max Conc. mM)
form powder
color white to beige

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

2-(5-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-N-(2-methoxyphenyl)butanamide price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML1729 SW044248 ≥98% (HPLC) 522650-83-5 5MG $95.7 2022-05-15 Buy
Sigma-Aldrich SML1729 SW044248 ≥98% (HPLC) 522650-83-5 25MG $386 2022-05-15 Buy
Cayman Chemical 23459 SW044248 ≥98% 522650-83-5 5mg $63 2024-03-01 Buy
Cayman Chemical 23459 SW044248 ≥98% 522650-83-5 10mg $113 2024-03-01 Buy
Cayman Chemical 23459 SW044248 ≥98% 522650-83-5 25 mg $219 2024-03-01 Buy
Product number Packaging Price Buy
SML1729 5MG $95.7 Buy
SML1729 25MG $386 Buy
23459 5mg $63 Buy
23459 10mg $113 Buy
23459 25 mg $219 Buy

2-(5-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-N-(2-methoxyphenyl)butanamide Chemical Properties,Uses,Production

Uses

2-((5-Ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)thio)-N-(2-methoxyphenyl)butanamide is a useful intermediate for organic synthesis and other chemical processes.

Biochem/physiol Actions

SW044248 is a cell permeable, indolotriazine-based compound that selectively inhibits topoisomerase 1 (Top 1), but not Top 2, catalyzed DNA decatenation in a manner distinct from that of camptothecin (Cat. Nos. 208925 & C9911). SW044248 is shown to exhibit antiproliferation efficacy against a subset of non-small-cell lung cancer (NSCLC) cultures (IC50 <5>10 μM) derived from the same patient as HCC4017.

2-(5-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-N-(2-methoxyphenyl)butanamide Preparation Products And Raw materials

Raw materials

Preparation Products

2-(5-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-N-(2-methoxyphenyl)butanamide Suppliers

Global( 59)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054 trendseenbio@gmail.com China 11681 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525 masar@topule.com China 8474 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131981 58
Shanghai Boyle Chemical Co., Ltd. sales@boylechem.com China 2923 55
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7553 61
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4863 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
InvivoChem 		58
TargetMol Chemicals Inc. 		58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		58
Wuhan Topule Biopharmaceutical Co., Ltd 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58
Shanghai Boyle Chemical Co., Ltd. 55
Haoyuan Chemexpress Co., Ltd. 61
MedChemexpress LLC 58

2-(5-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-N-(2-methoxyphenyl)butanamide Spectrum

2-(5-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-N-(2-methoxyphenyl)butanamide(522650-83-5)1HNMR

522650-83-5(2-(5-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-N-(2-methoxyphenyl)butanamide)Related Search:

2-butylsulfinyl-4-phenyl-6-thiophen-2-ylthieno[5,4-b]pyridin-3-amine 4-Chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-benzenesulfonamide SW076956
2-(5-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-N-(2-methoxyphenyl)butanamide SW-044248
2-(5-Ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfanyl)-N-(2-methoxy-phenyl )-butyramide SW044248 >=98% (HPLC) Butanamide, 2-[(5-ethyl-5H-1,2,4-triazino[5,6-b]indol-3-yl)thio]-N-(2-methoxyphenyl)- SW-044248, >98% CS-2302 SW 044248;SW044248 SW 044248,Topoisomerase,inhibit,SW-044248,SW044248,Inhibitor 522650-83-5