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KETANSERIN TARTRATE

KETANSERIN TARTRATE Structure
KETANSERIN TARTRATE structure
CAS No.
83846-83-7
Chemical Name:
KETANSERIN TARTRATE
Synonyms
kjk-945;R 41468;R41468 tartrate;Ketanserin Tartrat;Ketanserinetartrate;KETANSERIN TARTRATE;R 41468 TARTRATE SALT;quinazoline-2,4(1H,3H);KETANSERIN TARTRATE SALT;3-(2-(4-(4-Fluorobenzoyl)
CBNumber:
CB8415888
Molecular Formula:
C26H28FN3O9
Molecular Weight:
545.52
MDL Number:
MFCD11864992
MOL File:
83846-83-7.mol
MSDS File:
SDS
Last updated:2023-06-30 15:45:59
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KETANSERIN TARTRATE Properties

Melting point 183～186℃
storage temp. 2-8°C
solubility ethanol: 3.3mg/mL
form solid
color white
Water Solubility Soluble to 10 mM in water
CAS DataBase Reference 83846-83-7(CAS DataBase Reference)
FDA UNII 645498QK7H

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P301+P310
Hazard Codes  T
Risk Statements  25
Safety Statements  22-36/37/39-45
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  VA1411195
HazardClass  6.1
HS Code  29335990
Toxicity LD50 oral in rat: 129mg/kg
NFPA 704
0
2 0

KETANSERIN TARTRATE price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S006 Ketanserin (+)-tartrate salt ≥97%, solid 83846-83-7 10mg $87.6 2024-03-01 Buy
Sigma-Aldrich S006 Ketanserin (+)-tartrate salt ≥97%, solid 83846-83-7 50mg $279 2024-03-01 Buy
Sigma-Aldrich 5.06271 Ketanserin Tartrate - CAS 83846-83-7 - Calbiochem 83846-83-7 50MG $126 2024-03-01 Buy
Alfa Aesar J62798 Ketanserin tartrate, 98+% 83846-83-7 250mg $390.65 2024-03-01 Buy
Cayman Chemical 22058 Ketanserin (tartrate) ≥98% 83846-83-7 50mg $81 2024-03-01 Buy
Product number Packaging Price Buy
S006 10mg $87.6 Buy
S006 50mg $279 Buy
5.06271 50MG $126 Buy
J62798 250mg $390.65 Buy
22058 50mg $81 Buy

KETANSERIN TARTRATE Chemical Properties,Uses,Production

Description

Ketanserin is a potent antagonist of the serotonin (5-HT) receptor that is selective for 5-HT2 (IC50 = 6.3 nM; Ki = 2.1 nM). It has no activity at 5-HT1 receptors but does have activity at histamine type 1, α1-adrenergic, and dopamine receptors with Ki values of 10, 10, and 220 nM, respectively. Ketanserin induces dose-dependent inhibition of contractile responses to 5-HT in isolated rat caudal artery, canine basilar, carotid, coronary and gastrosplenic arteries, and canine gastrosplenic and saphenous veins. Ketanserin (10 mg/kg/day) significantly decreases blood pressure (BP), blood pressure variability (BPV), and hypertensive organ damage in spontaneously hypertensive rats. Formulations containing ketanserin have been used to treat hypertension in early-onset preeclampsia.

Uses

Selective 5-HT2A serotonin receptor antagonist

Uses

coccidiostat

Biological Activity

Selective 5-HT 2A serotonin receptor antagonist; can also be used to discriminate between 5-HT 1D and 5-HT 1B receptor subtypes.

Biochem/physiol Actions

Selective 5-HT2 serotonin receptor antagonist. Ketanserin significantly reduces nicotine self-administration in rats, supporting an unexpected involvement of serotonin in nicotine addiction.

storage

Room temperature

KETANSERIN TARTRATE Preparation Products And Raw materials

Raw materials

Preparation Products

KETANSERIN TARTRATE Suppliers

Global( 141)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Bao Enluo International TradeCo.，LTD 		+86-17331933971 +86-17331933971 deasea125996@gmail.com China 2503 58
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 15928 58
Cangzhou Wanyou New Material Technology Co.,Ltd 		18631714998 sales@czwytech.com CHINA 906 58
career henan chemical co 		+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Zhengzhou Alfa Chemical Co.,Ltd 		+8618530059196 sale04@alfachem.cn China 12468 58
SIMAGCHEM CORP 		+86-13806087780 sale@simagchem.com China 17367 58
Hebei Binshare New Material Co. Ltd 		+8618633865755 china01@hbbinshare.com CHINA 969 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Hebei Zhanyao Biotechnology Co. Ltd 		15369953316 +8615369953316 admin@zhanyaobio.com China 2136 58
Hebei Lingding Biotechnology Co., Ltd. 		+86-18031140164 +86-19933155420 erin@hbldbiotech.com China 878 58
Supplier Advantage
Henan Bao Enluo International TradeCo.，LTD 		58
Shanghai Daken Advanced Materials Co.,Ltd 		58
Cangzhou Wanyou New Material Technology Co.,Ltd 		58
career henan chemical co 		58
Zhengzhou Alfa Chemical Co.,Ltd 		58
SIMAGCHEM CORP 		58
Hebei Binshare New Material Co. Ltd 		58
TargetMol Chemicals Inc. 		58
Hebei Zhanyao Biotechnology Co. Ltd 		58
Hebei Lingding Biotechnology Co., Ltd. 		58

View Lastest Price from KETANSERIN TARTRATE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
KETANSERIN TARTRATE pictures 2024-04-26 KETANSERIN TARTRATE
83846-83-7
 US $66.00-21.00 / kg 1kg 99% 300tons Hebei Dangtong Import and export Co LTD
KETANSERIN TARTRATE pictures 2023-06-19 KETANSERIN TARTRATE
83846-83-7
 US $50.00 / kg 1kg 99% 1000tons Henan Bao Enluo International TradeCo.，LTD
Ketanserin Tartrate pictures 2021-10-20 Ketanserin Tartrate
83846-83-7
 US $50.00 / KG 1KG 99% 9000kg/per week Hebei Lingding Biotechnology Co., Ltd.

83846-83-7(KETANSERIN TARTRATE)Related Search:

2-(4-BENZYLPIPERIDINO)-1-ETHANAMINE 4-BENZOYLPIPERIDINE HYDROCHLORIDE 4-(4'-Fluorobenzyl)piperidine Butanedioic acid,2,3-dihydroxy- (2R,3R)-, ammonium salt (1:) KETANSERIN TARTRATE
BENZOYLUREA 4-(4-Fluorobenzoyl)piperidine N-(2-Aminoethyl)piperidine 1-(4-FLUORO-PHENYL)-BUTAN-1-ONE Benzoyleneurea
Ketanserin 4'-Fluoropropiophenone 4-Benzylpiperidine 1-(4-FLUOROPHENYL)-2-METHYLPROPAN-1-ONE 5-Diethylamino-2-pentanone
CHEMBRDG-BB 4013122 3,4-DIHYDROQUINAZOLIN-2(1H)-ONE 3,4-DIHYDRO-3-METHYL-2(1H)-QUINAZOLINONE

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R 41468 R 41468 TARTRATE SALT 3-(2-(4-(p-fluorobenzoyl)-1-piperidinyl)ethyl)-2,4(1h,3h)-quinazolinedionel 4(1h,3h)-quinazolinedione,3-(2-(4-(4-fluorobenzoyl)-1-piperidinyl)ethyl)-( kjk-945 r-(r*,r*))-2,3-dihydroxybutanedioate(1:1) 3-[2-[4-(4-fluorobenzoyl)piperidino]ethyl]quinazoline-2,4(1H,3H)-dione [R-(R*,R*)]-tartrate KETANSERIN TARTRATE (R 41468) (SELECTIVE 5-HT2/5-HT1C SEROTONI Ketanserinetartrate R 41468 (+)-tartrate salt, 3-(2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl)-2,4(1H,3H)-quinazolinedione (+)-tartrate salt 3-[2-[4-(4-Fluorobenzoyl)piperidino]ethyl]-2,4-(1H,3H)-quinazolinedione tartrate Ketanserin Tartrat 3-(2-(4-(4-fluorobenzoyl)piperidin-1-yl)ethyl)quinazoline-2,4(1H,3H)-dione 2,3-dihydroxysuccinate 3-(2-(4-(4-Fluorobenzoyl) -dione 2,3-dihydroxysuccinate quinazoline-2,4(1H,3H) Ketanserin tartrate salt Morpholino 3-[2-(4-FLUOROBENZOYL)-1-PIPERDINYL]-ETHYL]-2,4(1H,3H)-QUINAZOLINEDIONE TARTRATE 3-[2-[4-(4-FLUOROBENZOYL)-1-PIPERDINYL]ETHYL]-2,4(1H,3H)-QUINAZOLINEDIONE 3-[2-[4-(4-FLUOROBENZOYL)-1-PIPERDINYL]ETHYL]-2,4(1H,3H)-QUINAZOLINEDIONE TARTRATE 3-[2-[4-(4-FLUOROBENZOYL)-1-PIPERIDINYL]ETHYL]-2,4[1H,3H]-QUINAZOLINEDIONE TARTRATE 3-(2-[4-(4-FLUOROBENZOYL)-1-PIPERIDINYL]ETHYL)-2,4(1H,3H)-QUINAZOLINEDIONE TARTRATE SALT KETANSERIN TARTRATE KETANSERIN TARTRATE SALT R41468 tartrate 3-[2-[4-[(4-fluorophenyl)-oxomethyl]-1-piperidin-1-iumyl]ethyl]-1H-quinazoline-2,4-dione Ketanserin tartrate (R41468 tartrate) Ketanserin Tartrate - CAS 83846-83-7 - Calbiochem Ketanserin Hydrogen Tartrate 2,4(1H,3H)-Quinazolinedione,3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]ethyl]-,(2R,3R)-2,3-dihydroxybutanedioate (1:1) 3-(2-(4-(4-Fluorobenzoyl)piperidin-1-yl)ethyl)quinazoline-2,4(1H,3H)-dione (2R,3R)-2,3-dihydroxysuccinate 83846-83-7 C22H22FN3O3C4H6O6 C26H28N3O9F C4H6O6C22H22FN3O3 C26H28FN3O9 Biochemicals and Reagents Enzyme Inhibitors Other Enzymes, Inhibitors, and Substrates Enzyme Inhibitors by Type BioChemical Serotonin Cardiovascular APIs Serotonin receptor