2-[[4-[(2'-Chloro[1,1'-biphenyl]-3-yl)methoxy]phenyl]sulfonyl]acetic acid
- CAS No.
- 2102196-57-4
- Chemical Name:
- 2-[[4-[(2'-Chloro[1,1'-biphenyl]-3-yl)methoxy]phenyl]sulfonyl]acetic acid
- Synonyms
- FAA1 agonist-1;GPR40 agonist 4;GPR-40 agonist 4,GPR40 agonist 4;2-[[4-[(2'-Chloro[1,1'-biphenyl]-3-yl)methoxy]phenyl]sulfony...;2-[4-({2'-chloro-[1,1'-biphenyl]-3-yl}methoxy)benzenesulfonyl]acetic acid;2-[[4-[(2'-Chloro[1,1'-biphenyl]-3-yl)methoxy]phenyl]sulfonyl]acetic acid;Acetic acid, 2-?[[4-?[(2'-?chloro[1,?1'-?biphenyl]?-?3-?yl)?methoxy]?phenyl]?sulfonyl]?-
- CBNumber:
- CB84635367
- Molecular Formula:
- C21H17ClO5S
- Molecular Weight:
- 416.87
- MDL Number:
- MFCD31619242
- MOL File:
- 2102196-57-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 2-[[4-[(2''-Chloro[1,1''-biphenyl]-3-yl)methoxy]phenyl]sulfonyl]aceticAcid | C327230 | 1mg | $50 |
| GPR40agonist4 98.69% | CS-0023823 | 5mg | $120 |
| GPR40agonist4 98.69% | CS-0023823 | 10mg | $180 |
| GPR40agonist4 98.69% | CS-0023823 | 25mg | $350 |
| GPR40agonist4 98.69% | CS-0023823 | 50mg | $550 |
| Melting point | 121 - 123°C |
|---|---|
| Boiling point | 644.4±55.0 °C(Predicted) |
| Density | 1.370±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | DMSO (Slightly, Sonicated), Methanol (Slightly) |
| form | Solid |
| pka | 2.58±0.10(Predicted) |
| color | White to Off-White |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
2-[[4-[(2'-Chloro[1,1'-biphenyl]-3-yl)methoxy]phenyl]sulfonyl]acetic acid price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | C327230 | 2-[[4-[(2''-Chloro[1,1''-biphenyl]-3-yl)methoxy]phenyl]sulfonyl]aceticAcid | 2102196-57-4 | 1mg | $50 | 2021-12-16 | Buy |
| ChemScene | CS-0023823 | GPR40agonist4 98.69% | 2102196-57-4 | 5mg | $120 | 2021-12-16 | Buy |
| ChemScene | CS-0023823 | GPR40agonist4 98.69% | 2102196-57-4 | 10mg | $180 | 2021-12-16 | Buy |
| ChemScene | CS-0023823 | GPR40agonist4 98.69% | 2102196-57-4 | 25mg | $350 | 2021-12-16 | Buy |
| ChemScene | CS-0023823 | GPR40agonist4 98.69% | 2102196-57-4 | 50mg | $550 | 2021-12-16 | Buy |
2-[[4-[(2'-Chloro[1,1'-biphenyl]-3-yl)methoxy]phenyl]sulfonyl]acetic acid Chemical Properties,Uses,Production
Uses
2-[[4-[(2''-Chloro[1,1''-biphenyl]-3-yl)methoxy]phenyl]sulfonyl]acetic Acid, is a potent free fatty acid receptor 1 (FFA1/ GPR40) agonist with a pEC50 of 7.54.
in vivo
Single oral administration of GPR40 agonist 4 (compound 20) robustly reduces the plasma glucose excursion and enhances insulin secretion during an oral glucose tolerance test (OGTT) in a dose-dependent manner from 1 to 10 mg/kg when GPR40 agonist 4 is dosed 60 min prior to the oral glucose challenge. The area under the curve of blood glucose (AUC0-120min) and blood insulin (AUC0-120min) reveal that the minimum effective dose of GPR40 agonist 4 is 3 mg/kg. The hyperglycemia state is also markedly improved in GPR40 agonist 4 (20 mg/kg) treated group[1].
2-[[4-[(2'-Chloro[1,1'-biphenyl]-3-yl)methoxy]phenyl]sulfonyl]acetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
2-[[4-[(2'-Chloro[1,1'-biphenyl]-3-yl)methoxy]phenyl]sulfonyl]acetic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32467 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471; | sales@sarms4muscle.com | China | 10473 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8615965530500 | nickzhang@hangyubiotech.com | China | 9923 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696,15000506266 15000506266 | China | 4833 | 55 | |
| Shanghaizehan biopharma technology co., Ltd. | 021-61350663 13052117465 | sales@zehanbiopharma.com | China | 977 | 55 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | +86-010-60279497 +86-15646567669 | sales01@cooperate-pharm.com | China | 137 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 89689 | 60 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 7999 | 62 |





