2-[[4-[(2'-Chloro[1,1'-biphenyl]-3-yl)methoxy]phenyl]sulfonyl]acetic acid

CAS No.
2102196-57-4
Chemical Name:
2-[[4-[(2'-Chloro[1,1'-biphenyl]-3-yl)methoxy]phenyl]sulfonyl]acetic acid
Synonyms
FAA1 agonist-1;GPR40 agonist 4;GPR-40 agonist 4,GPR40 agonist 4;2-[[4-[(2'-Chloro[1,1'-biphenyl]-3-yl)methoxy]phenyl]sulfony...;2-[4-({2'-chloro-[1,1'-biphenyl]-3-yl}methoxy)benzenesulfonyl]acetic acid;2-[[4-[(2'-Chloro[1,1'-biphenyl]-3-yl)methoxy]phenyl]sulfonyl]acetic acid;Acetic acid, 2-?[[4-?[(2'-?chloro[1,?1'-?biphenyl]?-?3-?yl)?methoxy]?phenyl]?sulfonyl]?-
CBNumber:
CB84635367
Molecular Formula:
C21H17ClO5S
Molecular Weight:
416.87
MDL Number:
MFCD31619242
MOL File:
2102196-57-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:25
Product description Number Pack Size Price
2-[[4-[(2''-Chloro[1,1''-biphenyl]-3-yl)methoxy]phenyl]sulfonyl]aceticAcid C327230 1mg $50
GPR40agonist4 98.69% CS-0023823 5mg $120
GPR40agonist4 98.69% CS-0023823 10mg $180
GPR40agonist4 98.69% CS-0023823 25mg $350
GPR40agonist4 98.69% CS-0023823 50mg $550

2-[[4-[(2'-Chloro[1,1'-biphenyl]-3-yl)methoxy]phenyl]sulfonyl]acetic acid Properties

Melting point 121 - 123°C
Boiling point 644.4±55.0 °C(Predicted)
Density 1.370±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMSO (Slightly, Sonicated), Methanol (Slightly)
form Solid
pka 2.58±0.10(Predicted)
color White to Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

2-[[4-[(2'-Chloro[1,1'-biphenyl]-3-yl)methoxy]phenyl]sulfonyl]acetic acid price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC C327230 2-[[4-[(2''-Chloro[1,1''-biphenyl]-3-yl)methoxy]phenyl]sulfonyl]aceticAcid 2102196-57-4 1mg $50 2021-12-16 Buy
ChemScene CS-0023823 GPR40agonist4 98.69% 2102196-57-4 5mg $120 2021-12-16 Buy
ChemScene CS-0023823 GPR40agonist4 98.69% 2102196-57-4 10mg $180 2021-12-16 Buy
ChemScene CS-0023823 GPR40agonist4 98.69% 2102196-57-4 25mg $350 2021-12-16 Buy
ChemScene CS-0023823 GPR40agonist4 98.69% 2102196-57-4 50mg $550 2021-12-16 Buy
Product number Packaging Price Buy
C327230 1mg $50 Buy
CS-0023823 5mg $120 Buy
CS-0023823 10mg $180 Buy
CS-0023823 25mg $350 Buy
CS-0023823 50mg $550 Buy

2-[[4-[(2'-Chloro[1,1'-biphenyl]-3-yl)methoxy]phenyl]sulfonyl]acetic acid Chemical Properties,Uses,Production

Uses

2-[[4-[(2''-Chloro[1,1''-biphenyl]-3-yl)methoxy]phenyl]sulfonyl]acetic Acid, is a potent free fatty acid receptor 1 (FFA1/ GPR40) agonist with a pEC50 of 7.54.

in vivo

Single oral administration of GPR40 agonist 4 (compound 20) robustly reduces the plasma glucose excursion and enhances insulin secretion during an oral glucose tolerance test (OGTT) in a dose-dependent manner from 1 to 10 mg/kg when GPR40 agonist 4 is dosed 60 min prior to the oral glucose challenge. The area under the curve of blood glucose (AUC0-120min) and blood insulin (AUC0-120min) reveal that the minimum effective dose of GPR40 agonist 4 is 3 mg/kg. The hyperglycemia state is also markedly improved in GPR40 agonist 4 (20 mg/kg) treated group[1].

2-[[4-[(2'-Chloro[1,1'-biphenyl]-3-yl)methoxy]phenyl]sulfonyl]acetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

2-[[4-[(2'-Chloro[1,1'-biphenyl]-3-yl)methoxy]phenyl]sulfonyl]acetic acid Suppliers

Global( 33)Suppliers
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TargetMol Chemicals Inc.
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Zhejiang J&C Biological Technology Co.,Limited
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Aladdin Scientific
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Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696,15000506266 15000506266 China 4833 55
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ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 7999 62
2-[[4-[(2'-Chloro[1,1'-biphenyl]-3-yl)methoxy]phenyl]sulfonyl]acetic acid FAA1 agonist-1 Acetic acid, 2-?[[4-?[(2'-?chloro[1,?1'-?biphenyl]?-?3-?yl)?methoxy]?phenyl]?sulfonyl]?- GPR40 agonist 4 2-[[4-[(2'-Chloro[1,1'-biphenyl]-3-yl)methoxy]phenyl]sulfony... GPR-40 agonist 4,GPR40 agonist 4 2-[4-({2'-chloro-[1,1'-biphenyl]-3-yl}methoxy)benzenesulfonyl]acetic acid 2102196-57-4 C21H17ClO5S