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HALAZEPAM CIV (200 MG) (AS)

CAS No.
23092-17-3
Chemical Name:
HALAZEPAM CIV (200 MG) (AS)
Synonyms
Paxipam;sch12041;SCH 12041;Halezepam;Schering 12041;HALAZEPAM CIV USP/EP/BP;HALAZEPAM CIV (200 MG) (AS);7-chloro-5-phenyl-1-(2,2,2-trifluoroethyl)-3H-1,4-benzodiazepin-2-one;2,2-trifluoroethyl)-2h-1,4-benzodiazepin-7-chloro-3-dihydro-5-phenyl-1-(2;2h-1,4-benzodiazepin-2-one,1,3-dihydro-7-chloro-5-phenyl-1-(2,2,2-trifluoroeth
CBNumber:
CB8501417
Molecular Formula:
C17H12ClF3N2O
Molecular Weight:
352.74
MDL Number:
MOL File:
23092-17-3.mol
Last updated:2023-06-08 09:02:26

HALAZEPAM CIV (200 MG) (AS) Properties

Melting point 164-166°
Boiling point 487.8±45.0 °C(Predicted)
Density 1.37±0.1 g/cm3(Predicted)
solubility DMF: 25 mg/ml; DMSO: 25 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Ethanol: 10 mg/ml; Methanol: 1 mg/ml
form A crystalline solid
pka 2.61±0.20(Predicted)
EWG's Food Scores 1
FDA UNII 320YC168LF
EPA Substance Registry System Halazepam (23092-17-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS09
Signal word  Warning
Hazard statements  H317-H412-H315
Precautionary statements  P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P273-P501-P264-P280-P302+P352-P321-P332+P313-P362
RIDADR  3249
HazardClass  6.1(b)
PackingGroup  III
Toxicity LD50 in mice: >4000 mg/kg orally (Steinman)
NFPA 704
0
2 0

HALAZEPAM CIV (200 MG) (AS) Chemical Properties,Uses,Production

Uses

A benzodiazepine derivative that possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. It is a precursor to Desmethyldiazepam (D291595) and is equal to or more effective than Diazepam (D416855) with a lower frequency of side effects. Controlled Substance.

Definition

ChEBI: Halazepam is an organic molecular entity.

brand name

Paxipam (Schering).

HALAZEPAM CIV (200 MG) (AS) Preparation Products And Raw materials

Raw materials

Preparation Products

1,3-Dihydro-7-chloro-5-phenyl-1-(2,2,2-trifluoroethyl)-2H-1,4-benzodiazepin-2-one HALAZEPAM CIV (200 MG) (AS) 2,2-trifluoroethyl)-2h-1,4-benzodiazepin-7-chloro-3-dihydro-5-phenyl-1-(2 2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-chloro-5-phenyl-1-(2,2,2-trifluoroethyl)- 2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-5-phenyl-1-(2,2,2-trifluoroethyl)- 2h-1,4-benzodiazepin-2-one,1,3-dihydro-7-chloro-5-phenyl-1-(2,2,2-trifluoroeth 7-Chloro-1,3-dihydro-5-phenyl-1-(2,2,2-trifluoroethyl)-2H-1,4-benzodiazepin-2-one 7-Chloro-5-phenyl-1-(2,2,2-trifluoroethyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one Halezepam Paxipam SCH 12041 sch12041 Schering 12041 7-Chloro-1-(2,2,2-trifluoroethyl)-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one 7-Chloro-1-(2,2,2-trifluoroethyl)-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one 7-chloro-5-phenyl-1-(2,2,2-trifluoroethyl)-3H-1,4-benzodiazepin-2-one HALAZEPAM CIV USP/EP/BP 23092-17-3 Pharmaceuticals Aromatics Heterocycles Intermediates & Fine Chemicals Neurochemicals