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ChemicalBook >> CAS DataBase List >>7,10-Methanophenanthridine-2-carboxamide, 5,6,6a,7,8,9,10,10a-octahydro-6-phenyl-

7,10-Methanophenanthridine-2-carboxamide, 5,6,6a,7,8,9,10,10a-octahydro-6-phenyl-

7,10-Methanophenanthridine-2-carboxamide, 5,6,6a,7,8,9,10,10a-octahydro-6-phenyl- Structure
7,10-Methanophenanthridine-2-carboxamide, 5,6,6a,7,8,9,10,10a-octahydro-6-phenyl- structure
CAS No.
1005095-06-6
Chemical Name:
7,10-Methanophenanthridine-2-carboxamide, 5,6,6a,7,8,9,10,10a-octahydro-6-phenyl-
Synonyms
WAY-324197;SIRT2-IN-11;6-Phenyl-5,6,6a,7,8,9,10,10a-octahydro-7,10-methanophenanthridine-2-carboxamide;7,10-Methanophenanthridine-2-carboxamide, 5,6,6a,7,8,9,10,10a-octahydro-6-phenyl-
CBNumber:
CB88391663
Molecular Formula:
C21H22N2O
Molecular Weight:
318.41
MDL Number:
MOL File:
1005095-06-6.mol
MSDS File:
SDS
Last updated:2026-07-16 07:06:08
Request For Quotation

7,10-Methanophenanthridine-2-carboxamide, 5,6,6a,7,8,9,10,10a-octahydro-6-phenyl- Properties

Boiling point 494.0±45.0 °C(Predicted)
Density 1+-.0.06 g/cm3(Predicted)
pka 16.93±0.40(Predicted)
form Solid
color White to off-white

7,10-Methanophenanthridine-2-carboxamide, 5,6,6a,7,8,9,10,10a-octahydro-6-phenyl- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0623801 SIRT2-IN-11 99.94% 1005095-06-6 5mg $102 2026-06-04 Buy
ChemScene CS-0623801 SIRT2-IN-11 99.94% 1005095-06-6 10mg $154 2026-06-04 Buy
ChemScene CS-0623801 SIRT2-IN-11 99.94% 1005095-06-6 25mg $308 2026-06-04 Buy
ChemScene CS-0623801 SIRT2-IN-11 99.94% 1005095-06-6 50mg $461 2026-06-04 Buy
ChemScene CS-0623801 SIRT2-IN-11 99.94% 1005095-06-6 100mg $693 2026-06-04 Buy
Product number Packaging Price Buy
CS-0623801 5mg $102 Buy
CS-0623801 10mg $154 Buy
CS-0623801 25mg $308 Buy
CS-0623801 50mg $461 Buy
CS-0623801 100mg $693 Buy

7,10-Methanophenanthridine-2-carboxamide, 5,6,6a,7,8,9,10,10a-octahydro-6-phenyl- Chemical Properties,Uses,Production

Uses

SIRT2-IN-11 (AEM1) is a selective SIRT2 inhibitor with an IC50 value of 18.5 μM. SIRT2-IN-11 p53-dependently induces apoptosis, activates expression of CDKN1A, PUMA and NOXA, and increases acetylation of p53. SIRT2-IN-11 can be used for the research of p53-related cancers[1].

IC 50

SIRT2: 18.5 μM (IC50); SIRT1: 118.4 μM (IC50)

References

[1] Hoffmann G, et al. A novel sirtuin 2 (SIRT2) inhibitor with p53-dependent pro-apoptotic activity in non-small cell lung cancer. J Biol Chem. 2014 Feb 21;289(8):5208-16. DOI:10.1074/jbc.M113.487736

7,10-Methanophenanthridine-2-carboxamide, 5,6,6a,7,8,9,10,10a-octahydro-6-phenyl- Preparation Products And Raw materials

Raw materials

Preparation Products

7,10-Methanophenanthridine-2-carboxamide, 5,6,6a,7,8,9,10,10a-octahydro-6-phenyl- Suppliers

Global( 15)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 9796 55
Zhejiang Huida Biotech Co., LTD 0571-89903022 18679456698 zilong@hizyme.com China 8001 58
Jinan Jiuli Biotechnology Co. , Ltd. 15865264761 486064515@qq.com China 4960 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27626 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 59929 58
Xi'an Kaixin Biotechnology Co., Ltd 029-68881181 13619217766 3495811982@qq.com China 2816 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Henan Alpha Chemical Co., Ltd. 0371-55013243 15324716602 2232176231@qq.com China 9997 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. 6206333 13167063860 anhua.mao@aladdin-e.com China 43293 58
Supplier Advantage
Shanghai YuanYe Biotechnology Co., Ltd. 60
Tianjin Kailiqi Biotechnology Co., Ltd. 55
Zhejiang Huida Biotech Co., LTD 58
Jinan Jiuli Biotechnology Co. , Ltd. 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
Bide Pharmatech Ltd. 58
Xi'an Kaixin Biotechnology Co., Ltd 58
TargetMol Chemicals Inc. 58
Henan Alpha Chemical Co., Ltd. 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. 58

View Lastest Price from 7,10-Methanophenanthridine-2-carboxamide, 5,6,6a,7,8,9,10,10a-octahydro-6-phenyl- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
SIRT2-IN-11 pictures 2026-07-15 SIRT2-IN-11
1005095-06-6
 $277.00-443.00 10g TargetMol Chemicals Inc.
  • SIRT2-IN-11 pictures
  • SIRT2-IN-11
    1005095-06-6
  • $277.00-443.00
  • TargetMol Chemicals Inc.

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7,10-Methanophenanthridine-2-carboxamide, 5,6,6a,7,8,9,10,10a-octahydro-6-phenyl- WAY-324197 6-Phenyl-5,6,6a,7,8,9,10,10a-octahydro-7,10-methanophenanthridine-2-carboxamide SIRT2-IN-11 1005095-06-6