epsilon-viniferin
- CAS No.
- 62218-08-0
- Chemical Name:
- epsilon-viniferin
- Synonyms
- e-viniferin;Ε-VINIFERIN;epsilon-viniferin;trans-ε-Viniferin;epsilion-Viniferin;ε-Viniferin Standard;(-)-trans-ε-viniferin;(-)-trans-epsilon-viniferin;ε ?Viniferin,ε-?Viniferin,Inhibitor,inhibit,Cytochrome P450,CYPs,ε?Viniferin;(2R)-2β-(4-Hydroxyphenyl)-3α-(3,5-dihydroxyphenyl)-4-[(E)-4-hydroxystyryl]-2,3-dihydrobenzofuran-6-ol
- CBNumber:
- CB91337184
- Molecular Formula:
- C28H22O6
- Molecular Weight:
- 454.47
- MDL Number:
- MFCD12964987
- MOL File:
- 62218-08-0.mol
Melting point | approximate 157℃ (dec.) |
---|---|
storage temp. | Store at -20°C |
solubility | Soluble in methanol; |
form | Powder |
color | Off-white to gray |
Water Solubility | sparingly soluble in water |
LogP | 3.802 (est) |
FDA UNII | 0K8Z2K6Y7O |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
epsilon-viniferin price More Price(15)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | PHL83550 | ε-Viniferin phyproof? Reference Substance | 62218-08-0 | 10MG | $333 | 2023-01-07 | Buy |
Cayman Chemical | 25737 | trans-ε-Viniferin | 62218-08-0 | 500μg | $62 | 2024-03-01 | Buy |
Cayman Chemical | 25737 | trans-ε-Viniferin | 62218-08-0 | 1mg | $115 | 2024-03-01 | Buy |
Biosynth Carbosynth | FV30429 | epsilon-Viniferin | 62218-08-0 | 1mg | $140 | 2021-12-16 | Buy |
Biosynth Carbosynth | FV30429 | epsilon-Viniferin | 62218-08-0 | 2mg | $200 | 2021-12-16 | Buy |
epsilon-viniferin Chemical Properties,Uses,Production
Description
trans-ε-Viniferin is a stilbene polyphenol and dimer of trans-resveratrol that has been found in various red wines and has diverse biological activities. It induces disaggregation of aggregated amyloid-β (1-42) (Aβ42; ) fibrils in a cell-free assay and decreases Aβ42- and IL-1β-induced release of TNF-α and IL-6 in primary mouse neuron and astrocyte cocultures. trans-ε-Viniferin reduces cytotoxicity induced by truncated huntingtin (Htt) in PC12 cells (EC50 = 30 nM). It also reduces production of reactive oxygen species (ROS), mitochondrial dysfunction, and PGC-1α depletion and increases protein levels and deacetylase activity of sirtuin 3 (SIRT3) in cells expressing mutant Htt. trans-ε-Viniferin inhibits calcium-activated chloride channel currents in HT-29 cells (IC50 = ~1 μM). In vivo, trans-ε-viniferin (2 μg per animal) reduces rotavirus-induced secretory diarrhea in mice without affecting the rotaviral infection. Dietary administration of trans-ε-viniferin reduces hepatic triglyceride accumulation and body weight increases in a mouse model of diet-induced obesity.
Uses
ε-Viniferin is a stilbene extract posessing cytotoxic effects and may contain anti-cancer properties.
Definition
ChEBI: (-)-trans-epsilon-viniferin is a stilbenoid that is the (-)-trans-stereoisomer of epsilon-viniferin, obtained by cyclodimerisation of trans-resveratrol. It has a role as a metabolite. It is a member of 1-benzofurans, a polyphenol and a stilbenoid. It is functionally related to a trans-resveratrol. It is an enantiomer of a (+)-trans-epsilon-viniferin.
target
5-HT Receptor | MAO | Antifection
epsilon-viniferin Preparation Products And Raw materials
Raw materials
Preparation Products
epsilon-viniferin Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Aktin Chemicals, Inc. | 028-85159085 | info@aktinchem.com | CHINA | 1025 | 58 |
Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19994 | 58 |
LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
Chembest Research Laboratories Limited | +86-21-20908456 | sales@BioChemBest.com | China | 6008 | 61 |
BioBioPha Co., Ltd. | 0871-65217109 13211707573; | y.liu@mail.biobiopha.com | China | 5654 | 65 |
Chengdu Biopurify Phytochemicals Ltd. | +86-028-82633397 18982077548 | cwb1@biopurify.cn | China | 2376 | 60 |
View Lastest Price from epsilon-viniferin manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2023-02-24 | ε-Viniferin
62218-08-0
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. |
- ε-Viniferin
62218-08-0
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.