ChemicalBook >> CAS DataBase List >>(1-(4-Nitrophenyl)piperidin-3-yl)Methanol

(1-(4-Nitrophenyl)piperidin-3-yl)Methanol

CAS No.
166438-83-1
Chemical Name:
(1-(4-Nitrophenyl)piperidin-3-yl)Methanol
Synonyms
piperidin-3-yl);3-Piperidinemethanol, 1-(4-nitrophenyl)-;(1-(4-Nitrophenyl)piperidin-3-yl)Methanol
CBNumber:
CB92549775
Molecular Formula:
C12H16N2O3
Molecular Weight:
236.27
MDL Number:
MFCD11039478
MOL File:
166438-83-1.mol
MSDS File:
SDS
Last updated:2026-03-18 11:52:23
Product description Number Pack Size Price
(1-(4-Nitrophenyl)piperidin-3-yl)methanol W3619 250mg $124
(1-(4-Nitrophenyl)piperidin-3-yl)methanol 95+% 074766 1g $416
(1-(4-NITROPHENYL)PIPERIDIN-3-YL)METHANOL 95.00% CHM0167391 1G $1034.88
(1-(4-Nitrophenyl)piperidin-3-yl)methanol 95+% 074766 5g $1197
(1-(4-NITROPHENYL)PIPERIDIN-3-YL)METHANOL 95.00% CHM0167391 5G $2067.45

(1-(4-Nitrophenyl)piperidin-3-yl)Methanol Properties

storage temp. Sealed in dry,Room Temperature
Appearance Light yellow to yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338

(1-(4-Nitrophenyl)piperidin-3-yl)Methanol price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AK Scientific W3619 (1-(4-Nitrophenyl)piperidin-3-yl)methanol 166438-83-1 250mg $124 2021-12-16 Buy
Matrix Scientific 074766 (1-(4-Nitrophenyl)piperidin-3-yl)methanol 95+% 166438-83-1 1g $416 2021-12-16 Buy
American Custom Chemicals Corporation CHM0167391 (1-(4-NITROPHENYL)PIPERIDIN-3-YL)METHANOL 95.00% 166438-83-1 1G $1034.88 2021-12-16 Buy
Matrix Scientific 074766 (1-(4-Nitrophenyl)piperidin-3-yl)methanol 95+% 166438-83-1 5g $1197 2021-12-16 Buy
American Custom Chemicals Corporation CHM0167391 (1-(4-NITROPHENYL)PIPERIDIN-3-YL)METHANOL 95.00% 166438-83-1 5G $2067.45 2021-12-16 Buy
Product number Packaging Price Buy
W3619 250mg $124 Buy
074766 1g $416 Buy
CHM0167391 1G $1034.88 Buy
074766 5g $1197 Buy
CHM0167391 5G $2067.45 Buy

(1-(4-Nitrophenyl)piperidin-3-yl)Methanol Chemical Properties,Uses,Production

Synthesis

3-Piperidinemethanol

4606-65-9

4-Fluoronitrobenzene

350-46-9

(1-(4-Nitrophenyl)piperidin-3-yl)Methanol

166438-83-1

General procedure for the synthesis of (1-(4-nitrophenyl)piperidin-3-yl)methanol from 3-hydroxymethylpiperidine and p-fluoronitrobenzene: A mixture of piperidin-3-ylmethanol (2.0 g, 1.0 eq.) with 1-fluoro-4-nitrobenzene (2.94 g, 1.2 eq.) in DMSO (20 mL) was placed in an airtight vial with stirring and the reaction system heated up to 100 °C. The reaction process was monitored by thin layer chromatography (TLC) for 12 hours. Upon completion of the reaction, the reaction mixture was quenched with water and extracted with ethyl acetate (EtOAc). The organic layers were combined, dried over anhydrous sodium sulfate (Na2SO4), filtered and concentrated to afford (1-(4-nitrophenyl)piperidin-3-yl)methanol as a yellow solid (3.0 g, 75% yield). The structure of the product was confirmed by 1H NMR (400 MHz, DMSO-d6): δ 8.08 (d, 1H), 6.805 (d, 1H), 3.98 (m, 1H), 3.81 (d, 1H), 3.64 (m, 1H), 3.53 (m, 1H), 3.041 (m, 1H), 2.878 (m, 1H), 1.838 (m. 3H), 1.621 (m, 2H), 1.294 (d, 1H).

References

[1] Patent: WO2015/38417, 2015, A1. Location in patent: Page/Page column 100

(1-(4-Nitrophenyl)piperidin-3-yl)Methanol Preparation Products And Raw materials

Raw materials

Preparation Products

(1-(4-Nitrophenyl)piperidin-3-yl)Methanol Suppliers

Global( 28)Suppliers
Supplier Tel Email Country ProdList Advantage
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
Aladdin Scientific
tp@aladdinsci.com United States 52923 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131957 58
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42934 64
SynAsst Chemical. 021-60343070 China 12740 55
Bide Pharmatech Ltd. 400-400-164-7117 18317119277 product02@bidepharm.com China 39999 60
Cool Pharm, Ltd 021-60455363 18019463053 sales@coolpharm.com China 5896 58
Sichuan BaiPeng Biotechnology Co., Ltd. 028-65791793 18140026355 568470422@qq.com China 9997 58
Aikon International Limited 025-58859352 19370895928 dt3@aikonchem.com China 15491 58
Shanghai Jizhi Biochemical Technology Co. Ltd. 021-4009004166/18616739031 18616739031 3007523370@qq.com China 52678 58

(1-(4-Nitrophenyl)piperidin-3-yl)Methanol Spectrum

(1-(4-Nitrophenyl)piperidin-3-yl)Methanol piperidin-3-yl) 3-Piperidinemethanol, 1-(4-nitrophenyl)- 166438-83-1