GSK-J1 (lithiuM salt)
- CAS No.
- 2309668-29-7
- Chemical Name:
- GSK-J1 (lithiuM salt)
- Synonyms
- GSK-J1 (lithiuM salt)
- CBNumber:
- CB92715635
- Molecular Formula:
- C22H23N5O2.Li
- Molecular Weight:
- 396.39
- MDL Number:
- MOL File:
- 2309668-29-7.mol
| Product description | Number | Pack Size | Price |
| GSK-J1lithiumsalt | CS-3328 | 10mg | $70 |
| GSK-J1lithiumsalt | CS-3328 | 25mg | $115 |
| GSK-J1lithiumsalt | CS-3328 | 50mg | $205 |
| GSK-J1lithiumsalt | CS-3328 | 100mg | $340 |
GSK-J1 (lithiuM salt) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-3328 | GSK-J1lithiumsalt | 10mg | $70 | 2021-12-16 | Buy | |
| ChemScene | CS-3328 | GSK-J1lithiumsalt | 25mg | $115 | 2021-12-16 | Buy | |
| ChemScene | CS-3328 | GSK-J1lithiumsalt | 50mg | $205 | 2021-12-16 | Buy | |
| ChemScene | CS-3328 | GSK-J1lithiumsalt | 100mg | $340 | 2021-12-16 | Buy |
GSK-J1 (lithiuM salt) Chemical Properties,Uses,Production
Uses
GSK-J1 lithium salt is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A, with IC50 of 60 nM towards KDM6B.
IC 50
KDM6
References
[1] Kruidenier L, et al. A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response. Nature. 2012 Aug 16;488(7411):404-8. DOI:10.1038/nature11262
[2] Heinemann B, et al. Inhibition of demethylases by GSK-J1/J4. Nature. 2014 Oct 2;514(7520):E1-2 DOI:10.1038/nature13688
[3] Horton JR, et al. Characterization of a Linked Jumonji Domain of the KDM5/JARID1 Family of Histone H3 Lysine 4 Demethylases. J Biol Chem. 2016 Feb 5;291(6):2631-46. DOI:10.1074/jbc.M115.698449
GSK-J1 (lithiuM salt) Preparation Products And Raw materials
Raw materials
Preparation Products
GSK-J1 (lithiuM salt) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Haoyuan Chemexpress Co., Ltd. | 021-58950125 | info@chemexpress.com | China | 7552 | 61 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4861 | 58 |
| SPIRO PHARMA | eric_feng1954@126.com | China | 316 | 55 | |
| Absin Bioscience Inc. | 021-38015121 18438616290 | lanwu@univ-bio.com | China | 24731 | 58 |
| Chunchuang (Wuhan) Technology Co., Ltd | 15727060112 | yutianchun2007@126.com | China | 9803 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29641 | 58 |
| Guangzhou Junze Biotechnology Co., Ltd. | 17688489295 | CHINA | 188 | 58 |
| Supplier | Advantage |
|---|---|
| Haoyuan Chemexpress Co., Ltd. | 61 |
| MedChemexpress LLC | 58 |
| SPIRO PHARMA | 55 |
| Absin Bioscience Inc. | 58 |
| Chunchuang (Wuhan) Technology Co., Ltd | 58 |
| TargetMol Chemicals Inc. | 58 |
| Guangzhou Junze Biotechnology Co., Ltd. | 58 |
