ChemicalBook >> CAS DataBase List >>RS 102221 HYDROCHLORIDE
RS 102221 HYDROCHLORIDE
- CAS No.
- 185376-97-0
- Chemical Name:
- RS 102221 HYDROCHLORIDE
- Synonyms
- RS 102221;RS102221HCl;RS 102221 hydrochlor;RS 102221 HYDROCHLORIDE;4-dione hydrochloride hydrate;RS-102221 hydrochloride hydrate;8-[5-(2,4-Dimethoxy-5-(4-trifluoromethylphenylsulfonamido)phenyl-5-oxopentyl]-1,3,8-triazaspiro[4.;8-[5-(2,4-Dimethoxy-5-(4-trifluoromethylphenylsulphonam ido)phenyl-5-oxopentyl]-1,3,8-triazaspiro[4.5]decane-2;8-[5-(2,4-Dimethoxy-5-(4-trifluoromethylphenylsulfonamido)phenyl-5-oxopentyl]-1,3,8-triazaspiro[4.5]decane-2,4-dionehy;N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]dec-8-yl)-1-oxopentyl]-2,4-dimethoxyphenyl]-4-(trifluoromethyl)benzenesulfonamide
- CBNumber:
- CB9312416
- Molecular Formula:
- C27H31F3N4O7S
- Molecular Weight:
- 612.62
- MDL Number:
- MFCD09971036
- MOL File:
- 185376-97-0.mol
Last updated:2023-05-04 17:34:35
Density | 1.45 |
---|---|
storage temp. | Store at RT |
solubility | DMSO: ≥20mg/mL |
form | powder |
color | white |
FDA UNII | 48D22QR8GY |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26 |
WGK Germany | 3 |
RS 102221 HYDROCHLORIDE price More Price(4)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Tocris | 1050 | RS102221hydrochloride ≥98%(HPLC) | 185376-97-0 | 10 | $195 | 2021-12-16 | Buy |
Tocris | 1050 | RS102221hydrochloride ≥98%(HPLC) | 185376-97-0 | 50 | $818 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0006966 | RS-102221 95.00% | 185376-97-0 | 50MG | $1230.95 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0006966 | RS-102221 95.00% | 185376-97-0 | 10MG | $709.46 | 2021-12-16 | Buy |
RS 102221 HYDROCHLORIDE Chemical Properties,Uses,Production
Uses
RS 102221 Hydrochloride is a selective 5-HT2C receptor antagonist.
Definition
ChEBI: N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)-1-oxopentyl]-2,4-dimethoxyphenyl]-4-(trifluoromethyl)benzenesulfonamide is an aromatic ketone.
Biological Activity
Potent and selective 5-HT 2C antagonist (pK i = 8.7). Displays ~ 100-fold selectivity over the 5-HT 2A and 5-HT 2B subtypes and is > 100-fold selective over other 5-HT receptors, a- and b-adrenergic and muscarinic ACh receptors.
RS 102221 HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
RS 102221 HYDROCHLORIDE Suppliers
Global( 13)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
LETOPHARM LIMITED | +86-21-5821 5861 | sales@letopharm.com | China | 2384 | 58 |
Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 4182 | 55 |
Amatek Scientific Co. Ltd. | 0512-56316828 | info@amateksci.com | China | 28817 | 58 |
Jinan ponder chemical co. LTD | 0531-0000 | thinklifescience@163.com | China | 19690 | 58 |
Shanghai Universal Biotech Co.,Ltd | 18768175414 | gaojun@univ-bio.com | China | 24998 | 58 |
185376-97-0(RS 102221 HYDROCHLORIDE)Related Search:
RS 102221 HYDROCHLORIDE
8-[5-(2,4-Dimethoxy-5-(4-trifluoromethylphenylsulfonamido)phenyl-5-oxopentyl]-1,3,8-triazaspiro[4.5]decane-2,4-dionehy
RS102221HCl
8-[5-(2,4-Dimethoxy-5-(4-trifluoromethylphenylsulfonamido)phenyl-5-oxopentyl]-1,3,8-triazaspiro[4.
8-[5-(2,4-Dimethoxy-5-(4-Trifluoromethylphenylsulphonamido)Phenyl-5-Oxopentyl)]-1,3,8-Triazaspiro[4.5]Decane-2,4-Dione Hydrochloride
8-[5-(2,4-DIMETHOXY-5-(4-TRIFLUOROMETHYLPHENYLSULPHONAMIDO)PHENYL-5-OXOPENTYL)]-1,3,8-TRIAZASPIRO[4.5]DECANE-2,4-DIONE HYDROCHLORIDE
N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]dec-8-yl)-1-oxopentyl]-2,4-dimethoxyphenyl]-4-(trifluoromethyl)benzenesulfonamide
RS 102221
4-dione hydrochloride hydrate
8-[5-(2,4-Dimethoxy-5-(4-trifluoromethylphenylsulphonam ido)phenyl-5-oxopentyl]-1,3,8-triazaspiro[4.5]decane-2
RS-102221 hydrochloride hydrate
Benzenesulfonamide, N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]dec-8-yl)-1-oxopentyl]-2,4-dimethoxyphenyl]-4-(trifluoromethyl)-
RS 102221 hydrochlor
185376-97-0
C27H31F3N4O7S
C27H32ClF3N4O7S
C27H31F3N4O7SHCl