BPV(BIPY)
- CAS No.
- 1173697-60-3
- Chemical Name:
- BPV(BIPY)
- Synonyms
- BPV(BIPY);bpV(bipy), PTP and PTEN inhibitor;POTASSIUM BISPEROXO(BIPYRIDINE)OXOVANADATE (V)
- CBNumber:
- CB9400665
- Molecular Formula:
- C10H10KN2O6V
- Molecular Weight:
- 344.24
- MDL Number:
- MFCD01862577
- MOL File:
- Mol file
| Product description | Number | Pack Size | Price |
| bpV(bipy) ≥98%(51V-NMR) | AG-CR1-0047-M005 | 5mg | $70 |
BPV(BIPY) Chemical Properties,Uses,Production
Uses
bpV(bipy) hydrate is the inhibitor for phosphoinositide 3-phosphatase (PTEN) and protein tyrosine phosphatases (PTP-β and PTP-1B) with IC50s of 18, 60.3, and 164 nM, respectively[1].
Biological Activity
Cell permeable: no', 'Primary Target
phosphotyrosine phosphatase', 'Product does not compete with ATP.', 'Reversible: no', 'Target IC50: 18 nM against PTEN', 'Target Ki: 100 nM for phosphotyrosine phosphatase
References
[1] Schmid AC, et al., Bisperoxovanadium compounds are potent PTEN inhibitors. FEBS Lett. 2004 May 21;566(1-3):35-8. DOI:10.1016/j.febslet.2004.03.102
BPV(BIPY) Preparation Products And Raw materials
Raw materials
Preparation Products
BPV(BIPY) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
| Adipogen Life Sciences | 41-6192660-40 | info@adipogen.com | China | 5293 | 58 |
| Merck KGaA | 21-20338288 | ordercn@merckgroup.com | China | 6394 | 58 |
| Santa Cruz Biotechnology Inc | 021-60936350 | scbt@scbt.com | China | 6594 | 58 |
| Supplier | Advantage |
|---|---|
| Shanghai EFE Biological Technology Co., Ltd. | 58 |
| Adipogen Life Sciences | 58 |
| Merck KGaA | 58 |
| Santa Cruz Biotechnology Inc | 58 |
