2-Indancarboxylic acid
- CAS No.
- 25177-85-9
- Chemical Name:
- 2-Indancarboxylic acid
- Synonyms
- 2,3-Dihydro-1H-indene-2-carboxylic acid;INDAN-2-CARBOXYLIC ACID;2-Carboxyindane;CBI-BB ZERO/005363;Indancarboxylicacid;TIMTEC-BB SBB003945;2-Indancarboxylic acid;2-INDANECARBOXYLIC ACID;2-IndancarboxylicAcid>2-Indanylcarboxylic acid
- CBNumber:
- CB9412349
- Molecular Formula:
- C10H10O2
- Molecular Weight:
- 162.19
- MDL Number:
- MFCD00085095
- MOL File:
- 25177-85-9.mol
- MSDS File:
- SDS
| Melting point | 128-132 °C (lit.) |
|---|---|
| Boiling point | 192 °C / 18mmHg |
| Density | 1.0281 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| form | Crystalline Powder |
| pka | 4.65±0.20(Predicted) |
| color | White to cream or brown |
| InChI | 1S/C10H10O2/c11-10(12)9-5-7-3-1-2-4-8(7)6-9/h1-4,9H,5-6H2,(H,11,12) |
| InChIKey | XUDCMQBOWOLYCF-UHFFFAOYSA-N |
| SMILES | OC(=O)C1Cc2ccccc2C1 |
| CAS DataBase Reference | 25177-85-9(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29163990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
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| NFPA 704 |
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2-Indancarboxylic acid price More Price(52)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 595551 | Indan-2-carboxylic acid 97% | 25177-85-9 | 1g | $61.2 | 2023-06-20 | Buy |
| Sigma-Aldrich | 595551 | Indan-2-carboxylic acid 97% | 25177-85-9 | 5g | $234 | 2023-06-20 | Buy |
| TCI Chemical | I0532 | 2-Indancarboxylic Acid >98.0%(T) | 25177-85-9 | 1g | $31 | 2026-04-30 | Buy |
| TCI Chemical | I0532 | 2-Indancarboxylic Acid >98.0%(T) | 25177-85-9 | 5g | $100 | 2026-04-30 | Buy |
| Activate Scientific | AS74223 | Indane-2-carboxylic acid 98% | 25177-85-9 | 1g | $52 | 2026-06-04 | Buy |
2-Indancarboxylic acid Chemical Properties, Uses, Production
Chemical Properties
White powder
Synthesis
26453-01-0
25177-85-9
General procedure for the synthesis of 2-indenecarboxylic acid from 2,3-dihydro-1H-indene-2-carbonitrile: A mixture of 2,3-dihydro-1H-indene-2-carbonitrile (128) (55.1 g, 0.385 mol), concentrated hydrochloric acid (100 mL), and dioxane (500 mL) was stirred for 41 hours at 60-70°C. Upon completion of the reaction, the mixture was cooled and the dioxane was removed by evaporation to give a residue. The residue was suspended in 1 M hydrochloric acid (300 mL) and stirred at 20 °C for 15 hours. Subsequently, the solid product was collected by filtration, washed with water and dried to give 2-indenecarboxylic acid (129) (54.1 g, 87% yield) as a white solid. Melting point (EtOAc/petroleum ether recrystallization) 128 °C [literature value (Baeyer, A. Perkin W.H., Chem. Ber. 1884, 17, 122) mp 130.2 °C]; 1H NMR (δ): 10.50 (broad single peak, 1H, COOH), 7.14-7.25 (multiple peaks, 4H, H-4, H-5, H -6, H-7), 3.21-3.43 (multiple peaks, 5H, H-1, H-2, H-3).
References
[1] Patent: WO2006/104406, 2006, A1. Location in patent: Page/Page column 112
[2] Journal of Medicinal Chemistry, 2008, vol. 51, # 21, p. 6853 - 6865
2-Indancarboxylic acid Preparation Products And Raw materials
2-Indancarboxylic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 45000 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11592 | 64 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16307 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shanghai Xiannuo Biotechnology Co., Ltd. | 021-50718719 13918719472 | China | 978 | 58 |
View Latest Price from 2-Indancarboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-04 | Indan-2-carboxylic acid
25177-85-9
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
 |
2022-01-15 | 2,3-dihydro-1H-indene-2-carboxylicacid
25177-85-9
|
1KG | 98.6% | 100 tons | Honest Joy Holdings Limited
|
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 |
2021-07-02 | 2-INDANCARBOXYLIC ACID
25177-85-9
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- Indan-2-carboxylic acid
25177-85-9
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 2,3-dihydro-1H-indene-2-carboxylicacid
25177-85-9
- $0.00
- 98.6%
- Honest Joy Holdings Limited
-
- 2-INDANCARBOXYLIC ACID
25177-85-9
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
