THPN
- CAS No.
- 100079-26-3
- Chemical Name:
- THPN
- Synonyms
- THPN;THPN >=98% (HPLC);1-(3,4,5-Trihydroxyphenyl)-1-nonanone;1-Nonanone, 1-(3,4,5-trihydroxyphenyl)-
- CBNumber:
- CB94668607
- Molecular Formula:
- C15H22O4
- Molecular Weight:
- 266.33
- MDL Number:
- MFCD31656702
- MOL File:
- 100079-26-3.mol
- MSDS File:
- SDS
Last updated:2023-05-18 11:31:11
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P301+P312+P330 |
THPN price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1548 | THPN ≥98% (HPLC) | 100079-26-3 | 5MG | $117 | 2023-06-20 | Buy |
| Sigma-Aldrich | SML1548 | THPN ≥98% (HPLC) | 100079-26-3 | 25MG | $478 | 2023-06-20 | Buy |
| Tocris | 6017 | THPN ≥98%(HPLC) | 100079-26-3 | 25 | $316 | 2021-12-16 | Buy |
| Tocris | 6017 | THPN ≥98%(HPLC) | 100079-26-3 | 5 | $81 | 2021-12-16 | Buy |
| TRC | T430058 | THPN | 100079-26-3 | 2.5mg | $175 | 2021-12-16 | Buy |
THPN Chemical Properties,Uses,Production
Uses
THPN is a Nur77 agonist. THPN binds Nur77 and promotes translocation of the receptor to the mitochondria resulting in autophagy in melanoma cell lines.
General Description
THPN or 1-(3,4,5-Trihydroxyphenyl)nonan-1-one, is a derivative of cytosporone B.
Biochem/physiol Actions
THPN is potent nuclear receptor TR3 (Nur77) antagonist that induces autophagic cell death in melanoma. Co-application of THPN with Akt2 inhibitors significantly represses tumor growth in xenograft mouse model.
THPN Preparation Products And Raw materials
Raw materials
Preparation Products
THPN Suppliers
Global( 11)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Adamas Reagent, Ltd. | 400-6009262 16621234537 | zhangsn@titansci.com | China | 14113 | 59 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9926 | 65 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9414 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44894 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |
| Shanghai Aladdin Biochemical Technology Co.,Ltd. | +86-18521732826 | market@aladdin-e.com | China | 48617 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| Aladdin Scientific | 58 |
| Adamas Reagent, Ltd. | 59 |
| Sigma-Aldrich | 80 |
| BOC Sciences | 65 |
| Shanghai Hongye Biotechnology Co. Ltd | 58 |
| DC Chemicals | 58 |
| Energy Chemical | 58 |
| TargetMol Chemicals Inc. | 58 |
| Shanghai Aladdin Biochemical Technology Co.,Ltd. | 58 |
1-(3,4,5-Trihydroxyphenyl)-1-nonanone
THPN
1-Nonanone, 1-(3,4,5-trihydroxyphenyl)-
THPN >=98% (HPLC)
100079-26-3