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ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE

CAS No.
53-73-6
Chemical Name:
ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE
Synonyms
angiotensinamide;Angiotensin amide acetate;(ASN1,VAL5)-ANGIOTENSIN II;(Asn?,Val?)-Angiotensin II;ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE;hypertensin II, 1-amide-5-valyl;L-ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE;H-ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE-OH;[ASN1,VAL5]-ANGIOTENSIN II ACOH 4H2O;H2-ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE-OH
CBNumber:
CB9735222
Molecular Formula:
C49H70N14O11
Molecular Weight:
1031.17
MDL Number:
MFCD00167643
MOL File:
53-73-6.mol
MSDS File:
SDS
Last updated:2023-05-04 17:34:39

ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE Properties

Density 1.45±0.1 g/cm3(Predicted)
storage temp. -15°C
pka 3.56±0.10(Predicted)
FDA UNII 7WAL1X78KV
ATC code C01CX06

ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth Carbosynth FA109691 H-Asn-Arg-Val-Tyr-Val-His-Pro-Phe-OH 53-73-6 5mg $160 2021-12-16 Buy
Biosynth Carbosynth FA109691 H-Asn-Arg-Val-Tyr-Val-His-Pro-Phe-OH 53-73-6 10mg $250 2021-12-16 Buy
Biosynth Carbosynth FA109691 H-Asn-Arg-Val-Tyr-Val-His-Pro-Phe-OH 53-73-6 25mg $300 2021-12-16 Buy
Biosynth Carbosynth FA109691 H-Asn-Arg-Val-Tyr-Val-His-Pro-Phe-OH 53-73-6 50mg $450 2021-12-16 Buy
Biosynth Carbosynth FA109691 H-Asn-Arg-Val-Tyr-Val-His-Pro-Phe-OH 53-73-6 100mg $500 2021-12-16 Buy
Product number Packaging Price Buy
FA109691 5mg $160 Buy
FA109691 10mg $250 Buy
FA109691 25mg $300 Buy
FA109691 50mg $450 Buy
FA109691 100mg $500 Buy

ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE Chemical Properties,Uses,Production

Originator

Hypertensin,Ciba,W. Germany,1961

Definition

ChEBI: Angiotensinamide is an oligopeptide.

Manufacturing Process

48 mg (0.042 mmol) of L-asparaginyl-L-arginyl-L-valyl-L-tyrosyl-L-valyl-Lhistidyl- L-prolyl-L-phenylalanine methyl ester trihydrochloride are suspended in 0.5 ml of methanol, and treated gradually in the course of one hour with 0.3 ml of N-caustic soda solution (about 7 equivalents) so that the pH value of the solution is maintained between 10.5 and 11.5. After a further 30 minutes the solution is freed from methanol under vacuum at room temperature, adjusted with 1 N acetic acid to pH 7.4 and lyophilized. The residual mixture of free peptide and inorganic salts (79 mg) is fractionated by countercurrent distribution in the system butanol/0.1 N ammonium hydroxide. The pure octapeptide is obtained as a colorless powder which is soluble in water and methanol, more sparingly soluble in ethanol, and insoluble in acetone.

Therapeutic Function

Vasoconstrictor

General Description

Angiotensin amide (Hypertensin)is a synthetic polypeptide (1-L-aspariginyl-5-L-valine angiotensinoctapeptide) and has twice the pressor activity ofangiotensin II. It is pharmaceutically available as alyophilized powder for injection (0.5–2.5 mg diluted in500 mL of sodium chloride injection or 5% dextrose for injection)to be administered by continuous infusion. The pressoreffect of angiotensin is due to an increase in peripheralresistance; it constricts resistance vessels but has little or nostimulating action on the heart and little effect on the capacitancevessels. Angiotensin has been used as an adjunct invarious hypotensive states. It is mainly useful in controllingacute hypotension during administration of general anestheticsthat sensitize the heart to the effects of catecholamines.

ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 65)Suppliers
Supplier Tel Email Country ProdList Advantage
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715 admin@nexconn.com China 10247 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-87569265 +86-18612256290 1056@dideu.com China 3131 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-89586680 +86-18192503167 1026@dideu.com China 9126 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 28200 58
BOC Sciences
+16314854226 inquiry@bocsci.com United States 19743 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10523 58
Hebei Miaoyin Technology Co.,Ltd
+86-17367732028 +86-17367732028 kathy@hbyinsheng.com China 3582 58
Nanjing TGpeptide
+86-13347807150 +86-13347807150 support@tgpeptide.com China 3279 58
Zhejiang Hangyu API Co., Ltd
+8617531972939 anna@api-made.com China 2944 58

View Lastest Price from ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE USP/EP/BP pictures 2021-08-13 ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE USP/EP/BP
53-73-6
US $1.10 / g 1g 99.9% 100 Tons min Dideu Industries Group Limited
ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE pictures 2021-07-20 ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE
53-73-6
US $1.00-1.00 / KG 1g 99% 50tons Shaanxi Dideu Medichem Co. Ltd
ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE ACOH 4H2O (ASN1,VAL5)-ANGIOTENSIN II [ASN1,VAL5]-ANGIOTENSIN II ACOH 4H2O H-ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE-OH H2-ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE-OH 1-L-Asparagine-5-L-valineangiotensin II L-Asn-L-Arg-L-Val-L-Tyr-L-Val-L-His-L-Pro-L-Phe-OH 2-[[1-[2-[[2-[[2-[[2-[[2-[(2,4-diamino-4-keto-butanoyl)amino]-5-guanidino-pentanoyl]amino]-3-methyl-butanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methyl-butanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenyl-propionic acid L-ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE angiotensinamide hypertensin II, 1-amide-5-valyl 2-[[1-[2-[[2-[[2-[[2-[[5-(diaminomethylideneamino)-2-[(2,4-diamino-4-oxobutanoyl)amino]pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid 2-[[1-[2-[[2-[[2-[[2-[[5-[bis(azanyl)methylideneamino]-2-[[2,4-bis(azanyl)-4-oxo-butanoyl]amino]pentanoyl]amino]-3-methyl-butanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methyl-butanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidin-2-yl]carbonylamino]-3-phenyl-propanoic acid L-Phenylalanine, N-[1-[N-[N-[N-[N-(N(sup2)-L-asparaginyl-L-arginyl)-L-valyl]-L-tyrosyl]-L-valyl]-L-histidyl]-L-prolyl]- Angiotensin II, 1-L-asparagine-5-L-valine- ASN-ARG-VAL-TYR-VAL-HIS-PRO-PHE USP/EP/BP Angiotensin amide acetate Angiotensin amide acetate(53-73-6 Free base) (Asn?,Val?)-Angiotensin II 53-73-6