10-DEBC HYDROCHLORIDE

10-DEBC HYDROCHLORIDE structure

CAS No.: 201788-90-1

Chemical Name:: 10-DEBC HYDROCHLORIDE

Synonyms: aktX;CCG-206734;CCG 206734;10-DEBC HYDROCHLORIDE;10H-Phenoxazine-10-butanaMine,2-chloro-N,N-diethyl-;10-[4'-(N,N-Diethylamino)butyl]-2-chlorophenoxazinehydrochloride

CBNumber:: CB9838323

Molecular Formula:: C20H25ClN2O

Molecular Weight:: 344.88

MDL Number:: MFCD09038570

MOL File:: 201788-90-1.mol

Last updated:2023-04-23 13:52:06

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10-DEBC HYDROCHLORIDE Properties

Melting point	>178°C (dec.)
Boiling point	465.1±45.0 °C(Predicted)
Density	1.134±0.06 g/cm3(Predicted)
storage temp.	Desiccate at +4°C
form	White crystalline solid.
pka	10.46±0.25(Predicted)
color	White to Off-White

10-DEBC HYDROCHLORIDE price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Tocris	2558	10-DEBChydrochloride ≥99%(HPLC)	201788-90-1	10	$151	2021-12-16	Buy
Tocris	2558	10-DEBChydrochloride ≥99%(HPLC)	201788-90-1	50	$634	2021-12-16	Buy
Usbiological	254339	10-DEBC hydrochloride	201788-90-1	10mg	$409	2021-12-16	Buy
American Custom Chemicals Corporation	INB0001188	10-DEBC HYDROCHLORIDE 95.00%	201788-90-1	1MG	$148.05	2021-12-16	Buy
AK Scientific	9464CW	10-Debchydrochloride	201788-90-1	5mg	$229	2021-12-16	Buy

Product number	Packaging	Price	Buy
2558	10	$151	Buy
2558	50	$634	Buy
254339	10mg	$409	Buy
INB0001188	1MG	$148.05	Buy
9464CW	5mg	$229	Buy

10-DEBC HYDROCHLORIDE Chemical Properties,Uses,Production

Uses

10-DEBC Hydrochloride is an AKT inhibitor. Study shows that efficacy and selectivity of tumor cell killing by Akt inhibitors are substantially increased by chloroquine.

Biological Activity

Selective inhibitor of Akt/PKB. Inhibits IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5 μ M), suppressing downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein. Shows no activity at PDK1, SGK1 or PI 3-kinase. Inhibits cell growth (IC 50 ~ 2-6 μ M) and induces apoptosis in rhabdomyosarcoma cells.

10-DEBC HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

10-DEBC HYDROCHLORIDE Suppliers

Global( 11)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
MQ (shanghai) Pharmaceuticals Co., Ltd.	13761635123	1014988033@qq.com	China	4979	55
Changzhou Furuisi Biotechnology Co., Ltd	0519-85524369	3477467573@qq.com	China	8618	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24131	58
Nantong QuanYi Biotechnology Co., Ltd	0513-66337626 18051384581	sales@chemhifuture.com	China	4030	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
3B Pharmachem (Wuhan) International Co.,Ltd.	69
EMMX Biotechnology LLC	60
Shanghai EFE Biological Technology Co., Ltd.	58
MQ (shanghai) Pharmaceuticals Co., Ltd.	55
Changzhou Furuisi Biotechnology Co., Ltd	58
TargetMol Chemicals Inc.	58
Nantong QuanYi Biotechnology Co., Ltd	58

201788-90-1(10-DEBC HYDROCHLORIDE)Related Search:

Phenoxazine 10-DEBC HYDROCHLORIDE

10H-Phenoxazine-10-butanaMine,2-chloro-N,N-diethyl- 10-[4'-(N,N-Diethylamino)butyl]-2-chlorophenoxazinehydrochloride 10-DEBC HYDROCHLORIDE aktX CCG 206734 CCG-206734 201788-90-1 C20H25N2OClHCl