1-(2-Fluoro-5-nitrophenyl)ethan-1-one
- CAS No.
- 79110-05-7
- Chemical Name:
- 1-(2-Fluoro-5-nitrophenyl)ethan-1-one
- Synonyms
- 1-(2-Fluoro-5-nitrophenyl)ethanone;2'-FLUORO-5'-NITROACETOPHENONE;2'-Fluoro-5'-nitroacetophenone 96%;Ethanone,1-(2-fluoro-5-nitrophenyl)-;1-(2-Fluoro-5-nitrophenyl)ethan-1-one;1-(2-Fluoro-5-nitrophenyl)ethan-1-one ISO 9001：2015 REACH;1-(2-Fluoro-5-nitrophenyl)ethan-1-one, 3-Acetyl-4-fluoronitrobenzene
- CBNumber:
- CB9854396
- Molecular Formula:
- C8H6FNO3
- Molecular Weight:
- 183.14
- MDL Number:
- MFCD00277867
- MOL File:
- 79110-05-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 2'-Fluoro-5'-nitroacetophenone >98.0%(GC) | F1199 | 5g | $89 |
| 2'-Fluoro-5'-nitroacetophenone >98.0%(GC) | F1199 | 25g | $352 |
| 2''-Fluoro-5''-nitroacetophenone | F597575 | 500mg | $65 |
| 1-(2-Fluoro-5-nitrophenyl)ethanone 99.64% | CS-D1637 | 5g | $20 |
| 2'-Fluoro-5'-nitroacetophenone | 4654-3-X8 | 1g | $26 |
| More product size | |||
| Melting point | 53-54 °C |
|---|---|
| Boiling point | 241.0±20.0 °C(Predicted) |
| Density | 1.336±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| form | powder to crystal |
| color | White to Yellow to Green |
| InChI | InChI=1S/C8H6FNO3/c1-5(11)7-4-6(10(12)13)2-3-8(7)9/h2-4H,1H3 |
| InChIKey | BCXOSCQTHVTUET-UHFFFAOYSA-N |
| SMILES | C(=O)(C1=CC([N+]([O-])=O)=CC=C1F)C |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| HS Code | 2914790090 | |||||||||
| NFPA 704 |
|
1-(2-Fluoro-5-nitrophenyl)ethan-1-one price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | F1199 | 2'-Fluoro-5'-nitroacetophenone >98.0%(GC) | 79110-05-7 | 5g | $89 | 2026-04-30 | Buy |
| TCI Chemical | F1199 | 2'-Fluoro-5'-nitroacetophenone >98.0%(GC) | 79110-05-7 | 25g | $352 | 2026-04-30 | Buy |
| TRC | F597575 | 2''-Fluoro-5''-nitroacetophenone | 79110-05-7 | 500mg | $65 | 2021-12-16 | Buy |
| ChemScene | CS-D1637 | 1-(2-Fluoro-5-nitrophenyl)ethanone 99.64% | 79110-05-7 | 5g | $20 | 2021-12-16 | Buy |
| SynQuest Laboratories | 4654-3-X8 | 2'-Fluoro-5'-nitroacetophenone | 79110-05-7 | 1g | $26 | 2021-12-16 | Buy |
1-(2-Fluoro-5-nitrophenyl)ethan-1-one Chemical Properties,Uses,Production
Uses
2''-Fluoro-5''-nitroacetophenone
Synthesis
445-27-2
79110-05-7
A solution of 1-(2-fluorophenyl)ethanone (90.0 g, 652 mmol) with fuming nitric acid (53.1 mL) in concentrated sulfuric acid (129 mL) was slowly added dropwise to concentrated sulfuric acid (360 mL, 93-98%) pre-cooled to -42 °C under mechanical stirring. The reaction mixture was kept stirred at -42°C for 30 minutes. Upon completion of the reaction, the mixture was slowly poured into ice (1.3 kg) to quench the reaction. Subsequently, water (1 L) was added to precipitate the product from the solution. After all the ice melted, the precipitate was collected by filtration. The resulting solid was dissolved in EtOAc and the organic layer was washed sequentially with 5% aqueous Na2CO3 (2 x 300 mL), water (1 x 300 mL) and brine (1 x 300 mL), dried over anhydrous Na2SO4 and filtered. The filtrate was concentrated to give a yellow solid 1-(2-fluoro-5-nitrophenyl)ethanone (115 g, 97% yield).
References
[1] Patent: WO2012/139425, 2012, A1. Location in patent: Page/Page column 117
[2] Patent: WO2011/44184, 2011, A1. Location in patent: Page/Page column 99-100
[3] Patent: US2004/122237, 2004, A1. Location in patent: Page 388
[4] Journal of Heterocyclic Chemistry, 1991, vol. 28, # 3, p. 673 - 683
[5] Patent: US2002/151715, 2002, A1
1-(2-Fluoro-5-nitrophenyl)ethan-1-one Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20124 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Fluoropharm Co., Ltd. | +86-0571-85586753 +86-13336034509 | sales@fluoropharm.com | China | 1445 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29819 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10000 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
View Lastest Price from 1-(2-Fluoro-5-nitrophenyl)ethan-1-one manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-09-25 | 1-(2-Fluoro-5-nitrophenyl)ethan-1-one
79110-05-7
|
US $100.00-1.00 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2020-02-26 | 1-(2-Fluoro-5-nitrophenyl)ethan-1-one
79110-05-7
|
US $0.00-0.00 / Kg | 1KG | 99.0% | 100 tons | Shaanxi Dideu Medichem Co. Ltd | |
 |
2019-07-06 | 1-(2-Fluoro-5-nitrophenyl)ethan-1-one
79110-05-7
|
US $2.00 / kg | 1kg | 99% | 100kg | Career Henan Chemical Co |
-
- 1-(2-Fluoro-5-nitrophenyl)ethan-1-one
79110-05-7
- US $100.00-1.00 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 1-(2-Fluoro-5-nitrophenyl)ethan-1-one
79110-05-7
- US $0.00-0.00 / Kg
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- 1-(2-Fluoro-5-nitrophenyl)ethan-1-one
79110-05-7
- US $2.00 / kg
- 99%
- Career Henan Chemical Co
