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ethyl salicylate

ethyl salicylate Structure
CAS No.
118-61-6
Chemical Name:
ethyl salicylate
Synonyms
ETHYL SALICYLATE;Mesotol;Ethyl salicyclate;Salotan;salethyl;Sal Ethyl;Ethyl Liu;FEMA 2458;salicylicether;Ethylsalicylat
CBNumber:
CB1723193
Molecular Formula:
C9H10O3
Molecular Weight:
166.17
MOL File:
118-61-6.mol
MSDS File:
SDS
Modify Date:
2025/7/4 22:01:47

ethyl salicylate Properties

Melting point 1 °C (lit.)
Boiling point 234 °C (lit.)
Density 1.131 g/mL at 25 °C (lit.)
vapor pressure 0.05 mm Hg ( 25 °C)
refractive index n20/D 1.522(lit.)
FEMA 2458 | ETHYL SALICYLATE
Flash point 225 °F
storage temp. Store below +30°C.
solubility 0.25g/l
form Liquid
pka 9.93±0.10(Predicted)
color Clear colorless to pale yellow
Odor at 100.00 %. sweet wintergreen mint floral spicy balsam
Odor Type minty
biological source synthetic
explosive limit 1.1%(V)
Water Solubility slightly soluble
Merck 14,3850
JECFA Number 900
BRN 907659
Dielectric constant 8.6(21℃)
InChIKey GYCKQBWUSACYIF-UHFFFAOYSA-N
LogP 3.07 at 21.9℃
CAS DataBase Reference 118-61-6(CAS DataBase Reference)
NIST Chemistry Reference Benzoic acid, 2-hydroxy-, ethyl ester(118-61-6)
EPA Substance Registry System Ethyl salicylate (118-61-6)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P501
Hazard Codes  Xn,Xi
Risk Statements  22-36/38-52/53
Safety Statements  26-36
WGK Germany  1
RTECS  VO3000000
TSCA  Yes
HS Code  29182390
Toxicity LD50 orally in Rabbit: 1320 mg/kg LD50 dermal Rabbit > 5000 mg/kg
NFPA 704
1
2 0

ethyl salicylate price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) W245801 Ethyl salicylate ≥99%, FCC, FG 118-61-6 1SAMPLE-K ₹5141.88 2022-06-14 Buy
Sigma-Aldrich(India) W245801 Ethyl salicylate ≥99%, FCC, FG 118-61-6 1KG ₹6971.3 2022-06-14 Buy
Sigma-Aldrich(India) W245801 Ethyl salicylate ≥99%, FCC, FG 118-61-6 10KG ₹32345.1 2022-06-14 Buy
Sigma-Aldrich(India) W245801 Ethyl salicylate ≥99%, FCC, FG 118-61-6 25KG ₹70427.45 2022-06-14 Buy
Sigma-Aldrich 68291 Ethyl salicylate analytical standard 118-61-6 1ML ₹5932.1 2022-06-14 Buy
Product number Packaging Price Buy
W245801 1SAMPLE-K ₹5141.88 Buy
W245801 1KG ₹6971.3 Buy
W245801 10KG ₹32345.1 Buy
W245801 25KG ₹70427.45 Buy
68291 1ML ₹5932.1 Buy

ethyl salicylate Chemical Properties,Uses,Production

Description

Ethyl 2-hydroxdybenzoate is also known as Ethyl salicylate, which a kind of ester formed through the condensation between salicylic acid and ethanol. It can be used as a perfumery, artificial essence flavoring agent and used in cosmetics. It can also be used as analgesics, anti-inflammatory and antipyretic agents.

Occurrence

Reported found in raspberry, tomato, currants, rum, whiskey, red wine, plum brandy, Cape gooseberry, Feijoa fruit, papaya and scotch.

Production Methods

Ethyl salicylate is found naturally in currants and strawberries . It is manufactured commercially by the esterification of salicylic acid with ethyl alcohol.

Preparation

Ethyl 2-hydroxybenzoate is prepared by esterification of salicylic acid with ethyl alcohol and concentrated H2SO4 at 100°C in the presence of aluminum sulfate; by heating to the boil an alkaline solution of salicylic acid and ethyl p-toluenesulfonate.

General Description

Ethyl salicylate was hydrolysed to salicylic acid by the use of an extractive electrospray ionisation (EESI) device.

References

Sheu, Yaw-Wen, and Chein-Hsiun Tu. "Densities and viscosities of binary mixtures of ethyl acetoacetate, ethyl isovalerate, methyl benzoate, benzyl acetate, ethyl salicylate, and benzyl propionate with ethanol at T=(288.15, 298.15, 308.15, and 318.15) K." Journal of Chemical & Engineering Data 51.2 (2006): 545-553.
Filippa, Mauricio, Matías I. Sancho, and Estela Gasull. "Encapsulation of methyl and ethyl salicylates by β-cyclodextrin: HPLC, UV–vis and molecular modeling studies." Journal of pharmaceutical and biomedical analysis 48.3 (2008): 969-973.

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SALICYLIC ACID ETHYLESTER WITH GC 2-hydroxy-benzoicaciethylester Benzoicacid,2-hydroxy-,ethylester ethylhydroxylbenzoate o-(Ethoxycarbonyl)phenol Sal Ethyl salethyl RARECHEM AL BI 0029 SALICYLIC ACID ETHYL ESTER o-Hydroxybenzoic acid ethyl ester Salicylic acid ethyl Ethyl 2-hydroxybenzo Ethyl Liu Ethyl salicylate, 99+% 250GR Ethyl 2-Hydroxybenzoate 2-Hydroxybenzoic Acid Ethyl Ester Salicylic Acid Ethyl Ester salicylacidethylester Salicylic ether salicylicether salicylicethylester Salotan 2-ETHOXYCARBONYLPHENOL 2-HYDROXYBENZOIC ACID ETHYL ESTER FEMA 2458 LABOTEST-BB LT02097419 ETHYL 2-HYDROXYBENZOATE ETHYL O-HYDROXYBENZOATE Ethyl sallicylate Ethyl salicylate, 99+% ethylsalicylate,benzoicacid2-hydroxy-ethylester SALICYLIC ACID ETHYLESTER(SG) Ethylsalicylat ETHYL SALICYLATE 99+% FCC SALICYLIC ACID ETHYL ESTER, SECONDARY STANDARD Deferasirox Ethyl Salicylate Methyl Salicylate Impurity 6(Methyl Salicylate EP Impurity F) Salicylic Acid Impurity 1(Ethyl Salicylate) Ethyl Salicylate > ETHYL SALICYLATE FOR SYNTHESIS Ethyl 2-hydroxybenzoate USP/EP/BP Ethyl salicyclate Mesotol ETHYL SALICYLATE Salicylic Acid Ethylester(AS) Ethyl salicylate, 10 mM in DMSO 118-61-6 102-47-8 2HOC6H4CO2C2H5 HOC6H4COOC2H5 Building Blocks ACETATE Carbonyl Compounds C8 to C9 Esters Organic Building Blocks Heterocyclic Compounds Aromatic Esters Pharmaceutical Intermediates 118-61-6