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Azosemide

Azosemide Structure
CAS No.
27589-33-9
Chemical Name:
Azosemide
Synonyms
Diart;Luret;SK-110;ple1053;azosemid;Diurapid;AZOSEMIDE;Azosemidum;AZOSEMIDE HPLC;Azosemide USP/EP/BP
CBNumber:
CB5200179
Molecular Formula:
C12H11ClN6O2S2
Molecular Weight:
370.84
MOL File:
27589-33-9.mol
MSDS File:
SDS
Modify Date:
2025/9/25 19:11:34

Azosemide Properties

Melting point 218-221°
Boiling point 221°C (rough estimate)
Density 1.6843 (rough estimate)
refractive index 1.6100 (estimate)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility DMSO (Slightly), Methanol (Slightly, Heated)
form Solid
pka 3.58±0.10(Predicted)
color Crystals
InChI InChI=1S/C12H11ClN6O2S2/c13-9-5-10(15-6-7-2-1-3-22-7)8(12-16-18-19-17-12)4-11(9)23(14,20)21/h1-5,15H,6H2,(H2,14,20,21)(H,16,17,18,19)
InChIKey HMEDEBAJARCKCT-UHFFFAOYSA-N
SMILES C1(S(N)(=O)=O)=CC(C2=NNN=N2)=C(NCC2SC=CC=2)C=C1Cl
CAS DataBase Reference 27589-33-9(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H227
Precautionary statements  P501-P261-P270-P210-P271-P264-P280-P370+P378-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330-P302+P352+P312-P304+P340+P312-P403+P235
Toxicity LD50 orl-rat: 2545 mg/kg IYKEDH 18,666,87

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Azosemide Chemical Properties,Uses,Production

Description

Azosemide is a high-ceiling diuretic similiar in structure and profile to furosemide, albeit somewhat less potent and less bioavailable. It is useful in the treatment of congestive heart failure and similar edematous conditions.

Uses

Diuretic.

Definition

ChEBI: A sulfonamide that is benzenesulfonamide which is substituted at positions 2, 4, and 5 by chlorine, (2-thienylmethyl)amino and 1H-tetrazol-5-yl groups, respectively. It is a diuretic that has been used in the management of oedema and hyp rtension.

Safety Profile

Poison by intraperitoneal andintravenous routes. Moderately toxic by ingestion andsubcutaneous routes. An experimental teratogen. Whenheated to decomposition it emits toxic fumes of Cl-, SOx,and NOx.

Azosemide Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 121)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Medilink Pharmachem +91 (79) 3007-0133 New Delhi, India 424 50 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6100 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6257 58 Inquiry
Hebei Yanxi Chemical Co., Ltd. +8618531123677 China 5853 58 Inquiry
Tianjin Zhongxin Chemtech Co., Ltd. 86-22-66880623 +8618622897568 China 572 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29852 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49975 58 Inquiry
Hebei Mujin Biotechnology Co.,Ltd +8613288715578 China 12264 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354; +17819995354 United States 32432 58 Inquiry
Hefei TNJ Chemical Industry Co.,Ltd. +86-0551-65418671 +8618949823763 China 34563 58 Inquiry

Azosemide Spectrum

2-chloro-5-(1h-tetrazol-5-yl)-4-((2-thienylmethyl)amino)-benzenesulfonamid 2-chloro-5-(1h-tetrazol-5-yl)-n(sup4)-2-thenyl-sulfanilamid SK-110 2-chloro-5-(2H-1,2,3,4-tetrazol-5-yl)-4-(thiophen-2-ylmethylamino)benzenesulfonamide 2-chloro-5-(2H-tetrazol-5-yl)-4-(2-thienylmethylamino)benzenesulfonamide 2-chloro-5-(2H-tetrazol-5-yl)-4-(thiophen-2-ylmethylamino)benzenesulfonamide 2-chloro-5-(1h-tetrazol-5-yl)-n(sup4)-2-thenylsulfanilamide 5-(4’-chloro-5’-sulfamoyl-2’-thenylaminophenyl)-tetrazole azosemid ple1053 AZOSEMIDE 2-chloro-5-(1h-tetrazol-5-yl)-4-(2-thenylamino)benzenesulphonamide 2-CHLORO-5-(1H-TETRAZOL-5-YL)-4-((2-THIENYLMETHYL)AMINO)-BENZENESULFONAMIDE Azosemide(Chemical Name: 2-Chloro-5-(1h-Tertrazol-5-Yl)-N4-(2-Thenyl)) AZOSEMIDE HPLC Diart Diurapid Luret 2-Chloro-5-(1H-tetrazol-5-y1)-4-[(2-thienylmethyl)amino]benzenesulfona-Mide Azosemide USP/EP/BP Benzenesulfonamide, 2-chloro-5-(2H-tetrazol-5-yl)-4-[(2-thienylmethyl)amino]- Pharmaceutical Intermediate 98% Research Powder Azosemide Azosemidum Pharmaceutical Intermediate 98% Research Powder cas 27589-33-9 Azosemide Azosemide Solution, 100ppm Azosemide Solution, 1000ppm 2-Chloro-5-(1H-tetrazol-5-yl)-4-[(thiophen-2-ylmethyl)amino]benzenesulfonamide Azosemide, 10 mM in DMSO 27589-33-9 C12H11CIN6O2S2 C12H11ClN6O2S2