2-Bromoacetophenone
- CAS No.
- 70-11-1
- Chemical Name:
- 2-Bromoacetophenone
- Synonyms
- PHENACYL BROMIDE;2-BROMO-1-PHENYLETHANONE;A-BROMOACETOPHENONE;1-Phenyl-2-broMoethanone;NSC 9807;Stauffer 4644;AKOS BBS-00004003;Bromoacetylbenzene;-Bromoacetophenone;PhenacylBromide>
- CBNumber:
- CB6305185
- Molecular Formula:
- C8H7BrO
- Molecular Weight:
- 199.04
- MOL File:
- 70-11-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/10/13 20:07:10
Melting point | 48-51 °C (lit.) |
---|---|
Boiling point | 135 °C/18 mmHg (lit.) |
Density | 1.476 |
refractive index | 1.5700 (estimate) |
Flash point | >230 °F |
storage temp. | 2-8°C |
solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
form | Crystals or Powder |
color | White to dark green-brown |
Water Solubility | PRACTICALLY INSOLUBLE |
Merck | 14,1402 |
BRN | 606474 |
Stability | Stable. Incompatible with strong bases, strong oxidizing agents. Combustible. |
InChIKey | LIGACIXOYTUXAW-UHFFFAOYSA-N |
CAS DataBase Reference | 70-11-1(CAS DataBase Reference) |
NIST Chemistry Reference | Ethanone, 2-bromo-1-phenyl-(70-11-1) |
EPA Substance Registry System | Ethanone, 2-bromo-1-phenyl- (70-11-1) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS05 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H314 | |||||||||
Precautionary statements | P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363 | |||||||||
Hazard Codes | C | |||||||||
Risk Statements | 34-20/21/22 | |||||||||
Safety Statements | 26-36/37/39-45 | |||||||||
RIDADR | UN 2645 6.1/PG 2 | |||||||||
WGK Germany | 3 | |||||||||
F | 8-19 | |||||||||
Hazard Note | Corrosive | |||||||||
TSCA | Yes | |||||||||
HazardClass | 6.1 | |||||||||
PackingGroup | II | |||||||||
HS Code | 29143990 | |||||||||
NFPA 704 |
|
2-Bromoacetophenone price More Price(13)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 115835 | 2-Bromoacetophenone 98% | 70-11-1 | 5G | ₹3377.4 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 115835 | 2-Bromoacetophenone 98% | 70-11-1 | 100G | ₹5090 | 2022-06-14 | Buy |
Sigma-Aldrich | 77450 | 2-Bromoacetophenone for GC derivatization, LiChropur?, ≥99.0% | 70-11-1 | 10G | ₹6830.58 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 77450 | 2-Bromoacetophenone for GC derivatization, LiChropur?, ≥99.0% | 70-11-1 | 10G | ₹6830.58 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 115835 | 2-Bromoacetophenone 98% | 70-11-1 | 500G | ₹16194.2 | 2022-06-14 | Buy |
2-Bromoacetophenone Chemical Properties,Uses,Production
Chemical Properties
Off white-grey green crystaline powder
Uses
2-Bromoacetophenone is a brominated acteophenone derivative. 2-Bromoacetophenone has been shown to completely and irreversibly inactivate human liver aldehyde dehydrogenase (EC 1.2.1.3) isoenzymes E1 and E2. 2-Bromoacetophenone and its derivatives display some inhibitory activity on neutral protein tyrosine.inhibitors
Definition
ChEBI: An alpha-bromoketone that is acetophenone substituted by a bromo group at position 2.
General Description
A crystalline solid or a liquid with a sharp odor. Toxic by inhalation, ingestion and skin absorption. A severe eye irritant (a lachrymator). Used to make other chemicals.
Air & Water Reactions
Reacts slowly with moisture in air to form hydrogen bromide.
Reactivity Profile
2-Bromoacetophenone reacts slowly with metals causing mild corrosion.
Health Hazard
TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.
Fire Hazard
Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.
Purification Methods
Crystallise the bromide from EtOH, MeOH or pet ether (b 80-100o). [Tanner J Org Chem 52 2142 1987, Beilstein 7 IV 649.]
2-Bromoacetophenone Preparation Products And Raw materials
Raw materials
Preparation Products
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