ChemicalBook > Product Catalog >Chemical Reagents >Organic reagents >Bicyclic compound >ACETYLSHIKONIN

ACETYLSHIKONIN

CAS No.: 24502-78-1

Chemical Name:: ACETYLSHIKONIN

Synonyms: O-Acetylshikonin;Nsc110199;ACETYLSHIKONIN;Shikonin acetate;Shikonin, acetyl;(R)-acetyl shikonin;Acetylshikonin(natural);Acetylshikonin, 10 mM in DMSO;3-pentenyl]-5,8-dihydroxy-,(R)-;Racemic Acetyl Shikonin Labeled d7

CBNumber:: CB8317267

Molecular Formula:: C18H18O6

Molecular Weight:: 330.33

MOL File:: 24502-78-1.mol

MSDS File:: SDS

Modify Date:: 2026/7/27 17:00:41

Request For Quotation

ACETYLSHIKONIN Properties

Melting point	86°C
Boiling point	553.2±50.0 °C(Predicted)
Density	1.326±0.06 g/cm3(Predicted)
storage temp.	4°C, protect from light
solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form	Powder
pka	7.12±0.20(Predicted)
color	Brown to khaki
Stability	Hygroscopic
LogP	2.700 (est)
CAS DataBase Reference	24502-78-1(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Risk Statements	36/37/38
Safety Statements	26-36/37/39
Toxicity	mouse,LD50,intraperitoneal,41mg/kg (41mg/kg),BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)BEHAVIORAL: ATAXIA,Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 73, Pg. 193, 1977.

ACETYLSHIKONIN price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy

Product number	Packaging	Price	Buy

ACETYLSHIKONIN Chemical Properties,Uses,Production

Chemical Properties

Acetylshikonin is a biologically active compound with anti-cancer and anti-inflammatory activity, which is isolated from the roots of Lithospermum erythrorhizoma.

Biological Activity

Acetylshikonin is one naphthoquinone derivative isolated from the Lithospermum erythrorhizon, exhibits weak cytotoxicity against human umbilical vein endothelial cells (HUVECs) with IC50 of over 20 microM, exhibits the antiangiogenic and antitumorigenic effects by suppressing proliferation and angiogenic factors.
Acetylshikonin inhibits the generation of NADPH oxidase complex in the activation of respiratory burst of PMNs, but does not directly inhibit the activity of NADPH oxidase already generated.
Certain shikonin derivatives(such as Acetyl shikonin) act as modulators of the Nur77-mediated apoptotic pathway and identify a new shikonin-based lead that targets Nur77 for apoptosis induction.
Acetylshikonin, shikonin, and alkannin have accelerative effect on the proliferation of granulation tissue in rats.
Acetylshikonin isolated from Arnebia euchroma (Royle) Johnst cell suspension cultures exhibits specific in vivo and in vitro antitumor effects.
Acetylshikonin has inhibitory effect on the edematous response is due neither to the release of steroid hormones from the adrenal gland nor to the glucocorticoid activity, but probably partly to the suppression of mast cell degranulation and partly to protection of the vasculature from mediator challenge.
Acetylshikonin induces apoptosis of hepatitis B virus X protein-expressing human hepatocellular carcinoma cells via endoplasmic reticulum stress.

ACETYLSHIKONIN Preparation Products And Raw materials

Raw materials

Preparation Products

ACETYLSHIKONIN Suppliers

Global( 205)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Shaanxi Haibo Biotechnology Co., Ltd	+86-18629295024	China	996	58	Inquiry
career henan chemical co	+86-0371-86658258	China	29765	58	Inquiry
Chengdu GLP biotechnology Co Ltd	028-87075086 13350802083	CHINA	1824	58	Inquiry
Chengdu Biopurify Phytochemicals Ltd.	+86-28-82633860; +86-18080483897	China	4616	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	United States	32431	58	Inquiry
Hefei Hangang Pharmaceutical Technology Co., Ltd.	+8618062405514	China	10224	58	Inquiry
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +86-189 4982 3763	China	34524	58	Inquiry
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 17705817739	China	52445	58	Inquiry
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850 +8619957148339	China	24569	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354;	United States	38999	58	Inquiry

Supplier	Advantage
Shaanxi Haibo Biotechnology Co., Ltd	58
career henan chemical co	58
Chengdu GLP biotechnology Co Ltd	58
Chengdu Biopurify Phytochemicals Ltd.	58
TargetMol Chemicals Inc.	58
Hefei Hangang Pharmaceutical Technology Co., Ltd.	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
HANGZHOU LEAP CHEM CO., LTD.	58
TargetMol Chemicals Inc.	58

ACETYLSHIKONIN Spectrum

ACETYLSHIKONIN(24502-78-1)¹HNMR ACETYLSHIKONIN(24502-78-1)¹³CNMR ACETYLSHIKONIN(24502-78-1)IR1

24502-78-1(ACETYLSHIKONIN)Related Search:

Kaempferide Bengenin Atractylodin Neohesperidosyl dihydrochalcone Kaempferol

Myricetin Diosgenin Isorhamnetin Taxifolin PINOCEMBRIN

Alkannin 5,8-Dihydroxy-1,4-naphthoquinone ISOVALERYLSHIKONIN ISOBUTYRYLSHIKONIN ACETYLSHIKONIN

(beta,beta-Dimethylacryl)shikonin beta-Hydroxyisovalerylshikonin (2-Methyl-n-butyryl)shikonin

chevron_left

1of4

chevron_right

(+)-5,8-Dihydroxy-2-[(R)-1-acetoxy-4-methyl-3-pentenyl]-1,4-naphthoquinone (R)-1-(1,4-Dihydro-5,8-dihydroxy-1,4-dioxonaphthalen-2-yl)-4-methyl-3-pentenyl=acetate 2-[(R)-1-Acetoxy-4-methyl-3-pentenyl]-5,8-dihydroxy-1,4-naphthoquinone 1,4-Naphthoquinone, 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-, 2-acetate, (+)- Nsc110199 Shikonin, acetyl Shikonin acetate (+)-5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-1,4-naphthoquinone2-acet 4-naphthalenedione,2-(1-(acetyloxy)-4-methyl-3-pentenyl)-5,8-dihydroxy-( 4-naphthoquinone,5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-2-acetate 1,4-NAPHTHALENEDIONE,2-[1-(ACETYLOXY)-4-METHYL-3-PENTENYL]-5,8-DIHYDROXY-, (R)- ACETYLSHIKONIN (R)-1-(5,8-Dihydroxy-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-4-Methylpent-3-en-1-yl acetate ACETYLSHIKONIN: 1,4-NAPHTHALENEDIONE,2-[1-(ACETYLOXY)-4-METHYL-3-PENTENYL]-5,8-DIHYDROXY-, (R)-, 1,4-Naphthalenedione,2-[1-(acetyloxy)-4-methyl- 3-pentenyl]-5,8-dihydroxy-,(R)- Racemic Acetyl Shikonin Labeled d7 2,3-dimethoxybenzoic acid 2-(dimethylamino)ethyl ester hydrochloride 1,4-Naphthalenedione, 2-[(1R)-1-(acetyloxy)-4-methyl-3-penten-1-yl]-5,8-dihydroxy- (R)-acetyl shikonin Acetylshikonin, 10 mM in DMSO O-Acetylshikonin Acetylshikonin(natural) 24502-78-1 Miscellaneous Natural Products