ChemicalBook
Chinese Japanese Germany Korea

ACETYLSHIKONIN

ACETYLSHIKONIN
ACETYLSHIKONIN structure
CAS No.
24502-78-1
Chemical Name:
ACETYLSHIKONIN
Synonyms
Nsc110199;ACETYLSHIKONIN;Shikonin acetate;Shikonin, acetyl;O-Acetylshikonin;(R)-acetyl shikonin;3-pentenyl]-5,8-dihydroxy-,(R)-;Racemic Acetyl Shikonin Labeled d7;1,4-Naphthalenedione,2-[1-(acetyloxy)-4-methyl-;2,3-dimethoxybenzoic acid 2-(dimethylamino)ethyl ester hydrochloride
CBNumber:
CB8317267
Molecular Formula:
C18H18O6
Formula Weight:
330.33
MOL File:
24502-78-1.mol

ACETYLSHIKONIN Properties

Melting point:
86°C
Boiling point:
553.2±50.0 °C(Predicted)
Density 
1.326±0.06 g/cm3(Predicted)
pka
7.12±0.20(Predicted)
CAS DataBase Reference
24502-78-1(CAS DataBase Reference)
EWG's Food Scores
1
FDA UNII
ST04094S3X
SAFETY
  • Risk and Safety Statements
Risk Statements  36/37/38
Safety Statements  26-36/37/39

ACETYLSHIKONIN Chemical Properties,Uses,Production

Chemical Properties

Acetylshikonin is a biologically active compound with anti-cancer and anti-inflammatory activity, which is isolated from the roots of Lithospermum erythrorhizoma.

Biological Activity

Acetylshikonin is one naphthoquinone derivative isolated from the Lithospermum erythrorhizon, exhibits weak cytotoxicity against human umbilical vein endothelial cells (HUVECs) with IC50 of over 20 microM, exhibits the antiangiogenic and antitumorigenic effects by suppressing proliferation and angiogenic factors.
Acetylshikonin inhibits the generation of NADPH oxidase complex in the activation of respiratory burst of PMNs, but does not directly inhibit the activity of NADPH oxidase already generated.
Certain shikonin derivatives(such as Acetyl shikonin) act as modulators of the Nur77-mediated apoptotic pathway and identify a new shikonin-based lead that targets Nur77 for apoptosis induction.
Acetylshikonin, shikonin, and alkannin have accelerative effect on the proliferation of granulation tissue in rats.
Acetylshikonin isolated from Arnebia euchroma (Royle) Johnst cell suspension cultures exhibits specific in vivo and in vitro antitumor effects.
Acetylshikonin has inhibitory effect on the edematous response is due neither to the release of steroid hormones from the adrenal gland nor to the glucocorticoid activity, but probably partly to the suppression of mast cell degranulation and partly to protection of the vasculature from mediator challenge.
Acetylshikonin induces apoptosis of hepatitis B virus X protein-expressing human hepatocellular carcinoma cells via endoplasmic reticulum stress.

ACETYLSHIKONIN Preparation Products And Raw materials

Raw materials

Preparation Products


ACETYLSHIKONIN Suppliers

Global( 146)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29954 58
Chengdu GLP biotechnology Co Ltd
13350802083 028-87075086
scglp@glp-china.com CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd.
18482058008 18080483897
maggie@biopurify.com CHINA 2712 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 linda@hubeijusheng.com CHINA 28229 58
BOC Sciences
1-631-485-4226
1-631-614-7828 inquiry@bocsci.com United States 19752 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 37282 58
Shanghai Standard Technology Co., Ltd.
18502101150
+86-21-57127007-6606 ft-sales@nature-standard.com CHINA 1923 58
Wuhan ChemNorm Biotech Co.,Ltd.
18971486879 +86-27-8439 4403
+86-27-8439 4403 sales@chemnorm.com CHINA 2936 58
Target Molecule Corp
18019718960 781-999-5354
marketing@targetmol.com United States 19232 58

View Lastest Price from ACETYLSHIKONIN manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2020-05-26 Acetylshikonin
24502-78-1
US $0.00 / mg 20mg ≥98%(HPLC) 10 g Shanghai Standard Technology Co., Ltd.
2019-07-06 ACETYLSHIKONIN
24502-78-1
US $1.00 / KG 1KG 99% Customized career henan chemical co

ACETYLSHIKONIN Spectrum


24502-78-1(ACETYLSHIKONIN)Related Search:


Copyright 2017 © ChemicalBook. All rights reserved