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2-チオチミジン

2-チオチミジン 化学構造式
28585-51-5
CAS番号.
28585-51-5
化学名:
2-チオチミジン
别名:
2-チオチミジン;1-(2-デオキシ-β-D-erythro-ペントフラノシル)-2-チオチミン;1-[(2R,4S,5R)-4-ヒドロキシ-5-(ヒドロキシメチル)オキソラン-2-イル]-5-メチル-2-スルファニリデン-1,2,3,4-テトラヒドロピリミジン-4-オン
英語名:
2-Thiothymidine
英語别名:
2-THIOTHYMIDINE;Thymidine, 2-thio-;2-Thio-2'-deoxythymidine;2'-deoxy-5-methyl-2-thiouridine;1-(2-Deoxy-b-D-erythro-pentofuranosyl)-5-methyl-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone;1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-2-sulfanylidenepyrimidin-4-one;1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
CBNumber:
CB2693213
化学式:
C10H14N2O4S
分子量:
258.29
MOL File:
28585-51-5.mol

2-チオチミジン 物理性質

InChI:
InChI=1S/C10H14N2O4S/c1-5-3-12(10(17)11-9(5)15)8-2-6(14)7(4-13)16-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,17)/t6-,7+,8+/m0/s1
InChIKey:
PISWNSOQFZRVJK-XLPZGREQSA-N
SMILES:
OC[C@H]1O[C@@H](N2C=C(C)C(=O)NC2=S)C[C@@H]1O

安全性情報

2-チオチミジン 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

2-チオチミジン 化学特性,用途語,生産方法

使用

2-Thiothymidine is a mRNA therapy used for treatment of ornithine transcarbamylase deficiency.

主な応用

2-Thiothymidine is a hydrogen bond donor and acceptor that can be used as a substitute for thymine in the synthesis of DNA. 2-Thiothymidine has been shown to have successful in vivo treatment against bladder cancer and skin cells, as well as photochemical properties. It has been shown to inhibit the growth of prostate cancer cells by inhibiting DNA synthesis. 2-Thiothymidine binds to dna duplexes and polymerase chain reactions, which are important for replication of DNA. This drug also inhibits replication by preventing intramolecular hydrogen bonds from forming. 2-Thiothymidine is a nucleoside analog that is substituted for thymine during DNA synthesis. It inhibits the growth of prostate cancer cells by inhibiting DNA synthesis. It binds to dna duplexes and polymerase chain reactions, which are important for replication of DNA. This drug also inhibits replication by preventing intramolecular hydrogen bonds from forming.

2-チオチミジン 上流と下流の製品情報

原材料

準備製品

2-チオチミジン 生産企業

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28585-51-5(2-チオチミジン)キーワード:

5-メチル-2-チオウリジン 2-チオチミジン
  • 28585-51-5
  • 2-THIOTHYMIDINE
  • 1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-2-sulfanylidenepyrimidin-4-one
  • 2-Thio-2'-deoxythymidine
  • 2'-deoxy-5-methyl-2-thiouridine
  • 1-(2-Deoxy-b-D-erythro-pentofuranosyl)-5-methyl-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone
  • Thymidine, 2-thio-
  • 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
  • 2-チオチミジン
  • 1-(2-デオキシ-β-D-erythro-ペントフラノシル)-2-チオチミン
  • 1-[(2R,4S,5R)-4-ヒドロキシ-5-(ヒドロキシメチル)オキソラン-2-イル]-5-メチル-2-スルファニリデン-1,2,3,4-テトラヒドロピリミジン-4-オン
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