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LY367385

LY367385 化学構造式
198419-91-9
CAS番号.
198419-91-9
化学名:
LY367385
别名:
LY367385;LY-367385 塩酸塩
英語名:
LY 367385
英語别名:
LY 367385;LY367385,LY-367385;LY-367385 hydrochloride;SGIKDIUCJAUSRD-QMMMGPOBSA-N;(S)-4-[aMino(carboxy)Methyl]-3-Methylbenzoic acid;(S)-(+)-α-Amino-4-carboxy-2-methylbenzeneaceticacid;(S)-(+)-a-amino-4-carboxy-2-methylbenzeneacetic acid;(S)-(+)-α-Amino-4-carboxy-2-methylbenzeneacetic acid;Benzeneacetic acid, α-amino-4-carboxy-2-methyl-, (αS)-;Benzeneacetic acid, α-amino-4-carboxy-2-methyl-, (αS)-
CBNumber:
CB5200038
化学式:
C10H11NO4
分子量:
209.2
MOL File:
198419-91-9.mol

LY367385 物理性質

貯蔵温度 :
Desiccate at RT
溶解性:
H2O: >10mg/mL
外見 :
粉
色:
ホワイトからオフホワイト

安全性情報

WGK Germany  3

LY367385 価格 もっと(4)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01TOC1237 LY367385
LY 367385 		198419-91-9 10mg ￥67000 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01TOC1237 LY367385
LY 367385 		198419-91-9 50mg ￥282000 2024-03-01 購入
Sigma-Aldrich Japan L4420 LY-367385 塩酸塩 ≥98% (HPLC)
LY-367385 hydrochloride ≥98% (HPLC)		 198419-91-9 25mg ￥49600 2023-06-01 購入
Sigma-Aldrich Japan L4420 LY-367385 塩酸塩 ≥98% (HPLC)
LY-367385 hydrochloride ≥98% (HPLC)		 198419-91-9 5mg ￥16200 2018-12-25 購入

LY367385 化学特性,用途語,生産方法

使用

LY 367385 is a selective mGlu1a receptor antagonist used to treat inflammatory diseases (ie. multiple sclerosis) and neurodegenerative diseases (ie. Alzheimer’s) (1,2).

生物活性

A selective mGlu 1a receptor antagonist, with an IC 50 value of 8.8 μ M for blockade of quisqualate-induced phosphoinositide hydrolysis vs. > 100 μ M for mGlu 5a , and negligible action on group II and III receptors. Also available as part of the Group I mGlu Receptor Tocriset™ .

Biochem/physiol Actions

LY-367385 hydrochloride has an ability to inhibit induction of long-term potentiation (LTP).

LY367385 上流と下流の製品情報

原材料

準備製品

LY367385 生産企業

Global( 47)Suppliers
名前 電話番号 電子メール 国籍 製品カタログ 優位度
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 19892 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525
 masar@topule.com China 8474 58
Aladdin Scientific 		+1-833-552-7181
sales@aladdinsci.com United States 52927 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
 3bsc@sina.com China 15848 69
Ascent Scientific 4401179829988
customerservice@ascentscientific.co.uk United Kingdom 279 60
Sigma-Aldrich 021-61415566 800-8193336
 orderCN@merckgroup.com China 51471 80
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8449 60
BOC Sciences --
 info@bocsci.com USA 0 65
DC Chemicals 021-58447131 13564518121
 sales@dcchemicals.com China 9414 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912
 order@med-bio.cn China 8141 58

198419-91-9(LY367385)キーワード:

N,N-ジエチルベンズアミド (+)-Α-メチル-4-カルボキシフェニルグリシン ベンゼンメタノール, 4-[(1R)-1-アミノエチル]- 4-(カルボキシメチル)安息香酸 (RS)-4-カルボキシフェニルグリシン LY367385
  • 198419-91-9
  • (S)-(+)-ALPHA-AMINO-4-CARBOXY-2-METHYLBENZENEACETIC ACID
  • LY 367385
  • (S)-(+)-α-Amino-4-carboxy-2-methylbenzeneaceticacid
  • (S)-4-[aMino(carboxy)Methyl]-3-Methylbenzoic acid
  • (S)-(+)-a-amino-4-carboxy-2-methylbenzeneacetic acid
  • LY-367385 hydrochloride
  • (R)-(+)-alpha-Amino-4-carboxy-2-methylbenzeneacetic acid
  • LY-367385;(R)-(+)-ALPHA-AMINO-4-CARBOXY-2-METHYLBENZENEACETIC ACID
  • (S)-(+)-α-Amino-4-carboxy-2-methylbenzeneacetic acid
  • Benzeneacetic acid, α-amino-4-carboxy-2-methyl-, (αS)-
  • SGIKDIUCJAUSRD-QMMMGPOBSA-N
  • LY367385,LY-367385
  • Benzeneacetic acid, α-amino-4-carboxy-2-methyl-, (αS)-
  • LY367385
  • LY-367385 塩酸塩
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