Chinese english Germany Korea

TYR-D-ALA-GLY-PHE-D-LEU ACETATE SALT

化学構造式
94825-57-7
CAS番号.
94825-57-7
化学名:
别名:
英語名:
TYR-D-ALA-GLY-PHE-D-LEU ACETATE SALT
英語别名:
(D-alanine2,D-leucine5)enkephalin;(D-ALA2, D-LEU5)-ENKEPHALIN ACETATE;TYR-D-ALA-GLY-PHE-D-LEU ACETATE SALT;[D-ALA2, D-LEU5]-ENKEPHALIN ACETATE SALT;[D-Ala2, D-Leu5]-Enkephalin acetate salt,DADLE;(2R)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid
CBNumber:
CB5472798
化学式:
C31H43N5O9
分子量:
629.71
MOL File:
94825-57-7.mol

TYR-D-ALA-GLY-PHE-D-LEU ACETATE SALT 物理性質

貯蔵温度 :
−20°C

安全性情報

WGK Germany  3

TYR-D-ALA-GLY-PHE-D-LEU ACETATE SALT 価格 もっと(3)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
Sigma-Aldrich Japan E7131 ≥95% (HPLC)
[D-Ala2, D-Leu5]-Enkephalin acetate salt ≥95% (HPLC)		 94825-57-7 1mg ￥5140 2024-03-01 購入
Sigma-Aldrich Japan E7131 ≥95% (HPLC)
[D-Ala2, D-Leu5]-Enkephalin acetate salt ≥95% (HPLC)		 94825-57-7 5mg ￥15400 2024-03-01 購入
Sigma-Aldrich Japan E7131 ≥95% (HPLC)
[D-Ala2, D-Leu5]-Enkephalin acetate salt ≥95% (HPLC)		 94825-57-7 25mg ￥55500 2024-03-01 購入

TYR-D-ALA-GLY-PHE-D-LEU ACETATE SALT 化学特性,用途語,生産方法

使用

[D-Ala2, D-Leu5]-Enkephalin or DADLE has been used for use in immunocomplex kinetic assay, to determine the activation of p70s6k by DADLE in the cell clones D2 and DOE and in non-transfected parental Rat-1 fibroblasts and to assess the analgesic effect of WIN55,212-2 in mice.

一般的な説明

[D-Ala2, D-Leu5]-Enkephalin acetate salt, also called DADLE, is an analog of endogenous δ-opioid peptide encephalin, and is metabolically stable.

Biochem/physiol Actions

[D-Ala2, D-Leu5]-Enkephalin can induce hibernation in ground squirrels, during summers, when they do not normally hibernate. In multiorgan block preparation, it can prolong the survival time of organs such as, heart, lung, liver, spleen and kidney, up to 46hrs. It aids in tolerance development of myocardium to ischemia. It might have tissue protective role in central nervous system. It prevents and reverses methamphetamine (METH)-induced damage of dopaminergic terminals of brain. It prevents naltrexone-sensitive PC12 cell apoptosis in serum deprivation conditions. Thus, it might play an essential role in the survival of neurons and organs.

TYR-D-ALA-GLY-PHE-D-LEU ACETATE SALT 上流と下流の製品情報

原材料

準備製品

TYR-D-ALA-GLY-PHE-D-LEU ACETATE SALT 生産企業

Global( 6)Suppliers
名前 電話番号 電子メール 国籍 製品カタログ 優位度
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969
 isunpharm@qq.com China 4428 55
Sigma-Aldrich 021-61415566 800-8193336
 orderCN@merckgroup.com China 51471 80

94825-57-7()キーワード:

ロイシンエンケファリン 2-D-アラニン-5-D-ロイシンエンケファリン N-アセチル-D-ロイシン グリシル-D-ロイシン
  • 94825-57-7
  • [D-ALA2, D-LEU5]-ENKEPHALIN ACETATE SALT
  • TYR-D-ALA-GLY-PHE-D-LEU ACETATE SALT
  • (D-ALA2, D-LEU5)-ENKEPHALIN ACETATE
  • (D-alanine2,D-leucine5)enkephalin
  • [D-Ala2, D-Leu5]-Enkephalin acetate salt,DADLE
  • (2R)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid
Copyright 2017 © ChemicalBook. All rights reserved