TYR-D-ALA-GLY-PHE-D-LEU ACETATE SALT

TYR-D-ALA-GLY-PHE-D-LEU ACETATE SALT Struktur
94825-57-7
CAS-Nr.
94825-57-7
Englisch Name:
TYR-D-ALA-GLY-PHE-D-LEU ACETATE SALT
Synonyma:
(D-alanine2,D-leucine5)enkephalin;(D-ALA2, D-LEU5)-ENKEPHALIN ACETATE;TYR-D-ALA-GLY-PHE-D-LEU ACETATE SALT;[D-ALA2, D-LEU5]-ENKEPHALIN ACETATE SALT;[D-Ala2, D-Leu5]-Enkephalin acetate salt,DADLE;(2R)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid
CBNumber:
CB5472798
Summenformel:
C31H43N5O9
Molgewicht:
629.71
MOL-Datei:
94825-57-7.mol

TYR-D-ALA-GLY-PHE-D-LEU ACETATE SALT Eigenschaften

storage temp. 
−20°C

Sicherheit

WGK Germany  3

TYR-D-ALA-GLY-PHE-D-LEU ACETATE SALT Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

[D-Ala2, D-Leu5]-Enkephalin or DADLE has been used for use in immunocomplex kinetic assay, to determine the activation of p70s6k by DADLE in the cell clones D2 and DOE and in non-transfected parental Rat-1 fibroblasts and to assess the analgesic effect of WIN55,212-2 in mice.

Allgemeine Beschreibung

[D-Ala2, D-Leu5]-Enkephalin acetate salt, also called DADLE, is an analog of endogenous δ-opioid peptide encephalin, and is metabolically stable.

Biochem/physiol Actions

[D-Ala2, D-Leu5]-Enkephalin can induce hibernation in ground squirrels, during summers, when they do not normally hibernate. In multiorgan block preparation, it can prolong the survival time of organs such as, heart, lung, liver, spleen and kidney, up to 46hrs. It aids in tolerance development of myocardium to ischemia. It might have tissue protective role in central nervous system. It prevents and reverses methamphetamine (METH)-induced damage of dopaminergic terminals of brain. It prevents naltrexone-sensitive PC12 cell apoptosis in serum deprivation conditions. Thus, it might play an essential role in the survival of neurons and organs.

TYR-D-ALA-GLY-PHE-D-LEU ACETATE SALT Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


TYR-D-ALA-GLY-PHE-D-LEU ACETATE SALT Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 6)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969
isunpharm@qq.com China 4428 55
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80

94825-57-7()Verwandte Suche:


  • [D-ALA2, D-LEU5]-ENKEPHALIN ACETATE SALT
  • TYR-D-ALA-GLY-PHE-D-LEU ACETATE SALT
  • (D-ALA2, D-LEU5)-ENKEPHALIN ACETATE
  • (D-alanine2,D-leucine5)enkephalin
  • [D-Ala2, D-Leu5]-Enkephalin acetate salt,DADLE
  • (2R)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid
  • 94825-57-7
  • C31H43N5O9
  • Enkephalins
  • Peptides
  • Opioid Peptides
  • Biochemicals and Reagents
  • Amino Acids and Peptides
  • BioChemical
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