3,8aβ-ジメチル-5-メチレン-2,4,4aα,5,6,7,8,8a-オクタヒドロナフト[2,3-b]フラン-2-オン

3,8aβ-ジメチル-5-メチレン-2,4,4aα,5,6,7,8,8a-オクタヒドロナフト[2,3-b]フラン-2-オン 価格 もっと(3)

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入
関東化学株式会社(KANTO)	49060-65	アトラクチレノリドＩ Atractylenolide I	73069-13-3	10mg	￥107000	2024-03-01	購入
Sigma-Aldrich Japan	A2737	≥98% (HPLC) Atractylenolide I ≥98% (HPLC)	73069-13-3	10mg	￥47100	2024-03-01	購入
Sigma-Aldrich Japan	A2737	≥98% (HPLC) Atractylenolide I ≥98% (HPLC)	73069-13-3	50mg	￥129000	2023-06-01	購入

3,8aβ-ジメチル-5-メチレン-2,4,4aα,5,6,7,8,8a-オクタヒドロナフト[2,3-b]フラン-2-オン 化学特性,用途語,生産方法

説明

Atractylenolide I is a sesquiterpene that has been found in the rhizomes of A. macrocephala and has diverse biological activities, including anti-inflammatory, anti-angiogenic, anti-tumor, and antidepressant properties. It inhibits LPS-induced increases in TNF-α and nitric oxide (NO) production, as well as inducible nitric oxide synthase (iNOS) activity, in murine peritoneal macrophages (IC₅₀s = 23.1, 41, and 67.3 μM, respectively). Atractylenolide I reduces pouch fluid weight, inflammatory cell count, granuloma weight, and vascular index (ID₅₀s = 24.18, 19.46, 14.44, and 15.15 mg/kg, respectively) in a mouse air pouch granuloma model induced by Freund''s complete adjuvant (FCA). It also reduces the number of microvessels in the air pouch wall by 58.27% when administered at a dose of 20 mg/kg and reduces the blood levels of TNF-α, IL-1β, IL-6, VEGF, placenta growth factor (PlGF), and bFGF in a dose-dependent manner in a mouse model of FCA-induced granuloma. Atractylenolide I inhibits the growth of T-24, 5637, RT4, and 253J bladder cancer cells in vitro (IC₅₀s = 12.8-63.7 μM) and reduces tumor growth in T-24 and 253J mouse xenograft models in a dose-dependent manner. In a mouse model of depression induced by chronic unpredictable mild stress, atractylenolide I reverses stress-induced decreases in hippocampal levels of serotonin (5-HT; ) and norepinephrine and reduces immobility time in the forced swim and tail suspension tests in a dose-dependent manner, indicating antidepressant-like activity.

3,8aβ-ジメチル-5-メチレン-2,4,4aα,5,6,7,8,8a-オクタヒドロナフト[2,3-b]フラン-2-オン 上流と下流の製品情報

原材料

準備製品

3,8aβ-ジメチル-5-メチレン-2,4,4aα,5,6,7,8,8a-オクタヒドロナフト[2,3-b]フラン-2-オン 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
Shaanxi Haibo Biotechnology Co., Ltd	+undefined18602966907	qinhe02@xaltbio.com	China	1000	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3620	58
Chengdu GLP biotechnology Co Ltd	028-87075086 13350802083	scglp@glp-china.com	CHINA	1824	58
Chengdu Biopurify Phytochemicals Ltd.	+8618080483897	sales@biopurify.com	China	3424	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Shaanxi Pioneer Biotech Co., Ltd .	+8613259417953	sales@pioneerbiotech.com	China	3000	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58

73069-13-3(3,8aβ-ジメチル-5-メチレン-2,4,4aα,5,6,7,8,8a-オクタヒドロナフト[2,3-b]フラン-2-オン)キーワード:

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• 73069-13-3
• ATRACTYLENOLIDE-1
• 3,8aβ-Dimethyl-5-methylene-2,4,4aα,5,6,7,8,8a-octahydronaphtho[2,3-b]furan-2-one
• Eudesma-4(15),7(11),8-trien-12-olide
• 8,9-Dehydroasterolide
• (4aS,8aS)-4a,5,6,7,8,8a-Hexahydro-3,8a-dimethyl-5-methylenenaphtho[2,3-b]furan-2(4H)-one
• Atractylenolide Ⅰ
• Atractylenolide I, >99%
• Naphtho[2,3-b]furan-2(4H)-one,4a,5,6,7,8,8a-hexahydro-3,8a-dimethyl-5-methylene-, (4aS,8aS)-
• Atracylenolide I
• Extracted oil
• Methyl 4-ethyl-6,7-dimethoxy-9H-b-carboline-3-carboxylate
• STAT,Atractylenolide I,Janus kinase,Inhibitor,JAK,Toll-like Receptor (TLR),inhibit
• Dictyolactone I
• 3,8aβ-ジメチル-5-メチレン-2,4,4aα,5,6,7,8,8a-オクタヒドロナフト[2,3-b]フラン-2-オン
• アトラクチレノリドI
• オイデスマ-4(15),7(11),8-トリエン-12-オリド
• (4aS,8aS)-4a,5,6,7,8,8a-ヘキサヒドロ-3,8a-ジメチル-5-メチレンナフト[2,3-b]フラン-2(4H)-オン