タルマピモド 化学特性,用途語,生産方法
効能
免疫調節薬, マイトジェン活性化プロテインキナーゼ阻害薬
使用
Talmapimod is a p38 mitogen-activated protein (MAP) kinase inhibitor. Talmapimod reduced human myeloma cell growth in vivo both at early and advanced phases of the disease in mouse xenograft models. T
almapimod that blocks tumor necrosis factor-α, interleukin-1β, and cyclooxygenase-2 synthesis in patients with active rheumatoid arthritis (RA)
定義
ChEBI: An indolecarboxamide obtained by formal condensation of the carboxy group of 6-chloro-3-[(dimethylamino)(oxo)acetyl]-1-methylindole-5-carboxylic acid with the secondary amino group of (2S,5R)-1-[(4-fluorophenyl)methyl]-2,
-dimethylpiperazine. It is a potent inhibitor of MAPK and exhibits anti-cancer properties.
タルマピモド 上流と下流の製品情報
原材料
準備製品