InSolution Rapamycin - Calbiochem

 化学構造式
CAS番号.
化学名:
别名:
英語名:
InSolution Rapamycin - Calbiochem
英語别名:
InSolution Rapamycin - Calbiochem
CBNumber:
CB84817378
化学式:
分子量:
0
MOL File:
Mol file

InSolution Rapamycin - Calbiochem 物理性質

安全性情報

InSolution Rapamycin - Calbiochem 価格

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InSolution Rapamycin - Calbiochem 化学特性,用途語,生産方法

一般的な説明

Selectively inhibits the phosphorylation and activation of p70 S6 kinase (IC50 = 50 pM). Prevents the translational activation of IGF-II. Also prevents resting T-cells from entering the cell cycle, but does not directly arrest cell cycle progression. Shown to inhibit later signaling events, such as p110Rb phosphorylation, p34cdc2 kinase activation, and cyclin A synthesis. Exhibits strong binding to FK-506 binding proteins. Also reported to induce apoptosis in a murine B-cell line, to inhibit lymphokine-induced cell proliferation at the G1 phase, and to irreversibly arrest Saccharomyces cerevisiae cells in the G1 phase.

Biochem/physiol Actions

Primary TargetMammalian target of rapamycin (mTOR)

InSolution Rapamycin - Calbiochem 上流と下流の製品情報

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InSolution Rapamycin - Calbiochem 生産企業

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