ガベスチネル 化学特性,用途語,生産方法
効能
脳卒中治療薬, NMDA受容体拮抗薬
使用
Treatment of stroke (N-methylD-aspartate NMDA receptor antagonist).
生物活性
Highly potent and selective non-competitive antagonist acting at the strychnine-insensitive glycine binding site of the NMDA receptor-channel complex (K d = 0.8 nM). Displays > 1000-fold selectivity over NMDA, AMPA and kainate binding sites. Orally bioavailable and active in vivo .
安全性プロファイル
A poison by
intravenous route. When heated to
decomposition it emits toxic vapors of NOx
and Cl-.
ガベスチネル 上流と下流の製品情報
原材料
準備製品