Butorphanol tartrate

Butorphanol tartrate 구조식 이미지
카스 번호:
58786-99-5
상품명:
Butorphanol tartrate
동의어(영문):
torate;stadol;D00837;Moradol;torbutrol;NIH 10275;Torbugesic;Stadol (tn);oate(1:1)(salt);BUTORPHANOL TARTRATE
CBNumber:
CB0181202
분자식:
C25H35NO8
포뮬러 무게:
477.55
MOL 파일:
58786-99-5.mol

Butorphanol tartrate 속성

녹는점
217-219°
알파
D22 -64.0° (c = 0.4 in methanol)
저장 조건
2-8°C
CAS 데이터베이스
58786-99-5(CAS DataBase Reference)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xn
위험 카페고리 넘버 22-63
안전지침서 22-26-36/37/39
유엔번호(UN No.) 1544
WGK 독일 3
RTECS 번호 QC7795000
위험 등급 6.1(a)
포장분류 II
HS 번호 2933492250
독성 LD50 in mice, rats (mg/kg): 40-57, 17-20 i.v.; 395-527, 570-756 orally (Heel)
그림문자(GHS): GHS hazard pictogramsGHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H302 삼키면 유해함 급성 독성 물질 - 경구 구분 4 경고 GHS hazard pictograms P264, P270, P301+P312, P330, P501
H361 태아 또는 생식능력에 손상을 일으킬 것으로 의심됨 생식독성 물질 구분 2 경고 P201, P202, P281, P308+P313, P405,P501
예방조치문구:
P201 사용 전 취급 설명서를 확보하시오.
P308+P313 노출 또는 접촉이 우려되면 의학적인 조치· 조언를 구하시오.

Butorphanol tartrate C화학적 특성, 용도, 생산

개요

Butorphanol (tartrate) (Item No. 23812) is an analytical reference material categorized as an opioid. Butorphanol is regulated as a Schedule IV compound in the United States. This product is intended for research and forensic applications.

용도

Analgesic; antitussive.

정의

ChEBI: The (S,S)-tartaric acid salt of butorphanol. It is used for relief or moderate to severe pain.

Mechanism of action

Butorphanol is a strong agonist at κ opioid receptors, and through this interaction, it is five times more potent than morphine as an analgesic. The κagonists have a lower ceiling analgesic effect than full μ agonists; thus, they are not as effective in treating severe pain. Butorphanol is an antagonist at μ opioid receptors with approximately one-sixth the potency of naloxone. If given to a person addicted to a μ agonist, butorphanol will induce an immediate onset of abstinence syndrome.

부작용

Butorphanol has a different spectrum of side effects than μ opioid analgesics. Respiratory depression occurs. There is a lower ceiling on this effect, however, and it is not generally lethal, as is the case with high doses of μ agonists. Major side effects after normal analgesic doses are sedation, nausea, and sweating, as well as dysphoric (hallucinogenic) effects at higher doses. Butorphanol causes an increase in pulmonary arterial pressure and pulmonary vascular resistance. There is an overall increased workload on the heart, and it should not be used in patients with congestive heart failure or to treat pain from acute myocardial infarction. Butorphanol has low abuse potential and is not a scheduled drug.

Butorphanol tartrate 준비 용품 및 원자재

원자재

준비 용품


Butorphanol tartrate 공급 업체

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