N-[4-[4-(2,3-DICHLOROPHENYL)-1-PIPERAZINYL]BUTYL]-9H-FLUORENE-2-CARBOXAMIDE HYDROCHLORIDE

N-[4-[4-(2,3-DICHLOROPHENYL)-1-PIPERAZINYL]BUTYL]-9H-FLUORENE-2-CARBOXAMIDE HYDROCHLORIDE 구조식 이미지
카스 번호:
189060-98-8
상품명:
N-[4-[4-(2,3-DICHLOROPHENYL)-1-PIPERAZINYL]BUTYL]-9H-FLUORENE-2-CARBOXAMIDE HYDROCHLORIDE
동의어(영문):
Ngb-2904;Ngb 2904;NGB2904 HCl;NGB 2904 HYDROCHLORIDE;N-(4-(4-(2,3-Dichlorophenyl)-1-piperazinyl)butyl)-3-fluorenylcarboxamide;N-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butyl]-9H-fluorene-2-carboxamide;N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-9H-fluorene-2-carboxamide;9H-Fluorene-2-carboxamide, N-(4-(4-(2,3-dichlorophenyl)-1-piperazinyl)butyl)-;N-[4-[4-(2,3-DICHLOROPHENYL)-1-PIPERAZINYL]BUTYL]-9H-FLUORENE-2-CARBOXAMIDE HYDROCHLORIDE;addiction,NGB 2904,orally,active,cocaine,Dopamine Receptor,dopamine,inhibit,Inhibitor,selective
CBNumber:
CB02453431
분자식:
C28H29Cl2N3O
포뮬러 무게:
494.46
MOL 파일:
189060-98-8.mol

N-[4-[4-(2,3-DICHLOROPHENYL)-1-PIPERAZINYL]BUTYL]-9H-FLUORENE-2-CARBOXAMIDE HYDROCHLORIDE 속성

끓는 점
691.0±55.0 °C(Predicted)
밀도
1.264±0.06 g/cm3(Predicted)
저장 조건
Desiccate at +4°C
용해도
DMSO: 25 mM,Ethanol: 5 mM
산도 계수 (pKa)
14.70±0.20(Predicted)

안전

N-[4-[4-(2,3-DICHLOROPHENYL)-1-PIPERAZINYL]BUTYL]-9H-FLUORENE-2-CARBOXAMIDE HYDROCHLORIDE C화학적 특성, 용도, 생산

용도

NGB 2904 is a highly-selective D3DR antagonist.

생물학적 활성

Potent and selective dopamine D 3 receptor antagonist (K i values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D 3 , D 2 , 5-HT 2 , α 1 , D 4 , D 1 and D 5 receptors respectively). Potently antagonizes quinpirole-stimulated mitogenesis (IC 50 = 6.8 nM). Attenuates cocaine's rewarding effects and inhibits relapse to drug-seeking behavior.

N-[4-[4-(2,3-DICHLOROPHENYL)-1-PIPERAZINYL]BUTYL]-9H-FLUORENE-2-CARBOXAMIDE HYDROCHLORIDE 준비 용품 및 원자재

원자재

준비 용품


N-[4-[4-(2,3-DICHLOROPHENYL)-1-PIPERAZINYL]BUTYL]-9H-FLUORENE-2-CARBOXAMIDE HYDROCHLORIDE 공급 업체

글로벌( 18)공급 업체
공급자 전화 이메일 국가 제품 수 이점
TargetMol Chemicals Inc.
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3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
3bsc@sina.com China 15848 69
EMMX Biotechnology LLC 888-539-0666
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Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720
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ShangHai Biochempartner Co.,Ltd 17754423994 17754423994
2853530910@QQ.com China 8011 62
Energy Chemical 021-58432009 400-005-6266
marketing1@energy-chemical.com China 44894 58
InvivoChem 13549236410
sales@invivochem.cn China 6712 58
TargetMol Chemicals Inc. 4008200310
marketing@tsbiochem.com China 24131 58
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050
cindy.huang@synzest.com China 12007 58

N-[4-[4-(2,3-DICHLOROPHENYL)-1-PIPERAZINYL]BUTYL]-9H-FLUORENE-2-CARBOXAMIDE HYDROCHLORIDE 관련 검색:

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