C04742;AL12959;AL 12959;AL-12959;Icomucret;15(S)-HETE;(S)-15-HETE;JSFATNQSLKRBCI-VAEKSGALSA-N;15(S)-HETE MaxSpec Standard;15(S)-HETE Lipid Maps MS Standard
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NFPA 704
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15(S)-HETE C화학적 특성, 용도, 생산
용도
15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. In mammals, 15(S)-HETE is synthesized in the respiratory epithelium, leukocytes, and reticulocytes. 15(S)-HETE is present in μg/ml concentrations in the nasal secretions of allergic rhinitis.
정의
ChEBI: An optically active form of 15-HETE having 15(S)-configuration..
일반 설명
15(S)-HETE is a product of the arachidonic acid pathway. It is synthesized by the human lungs and airway epithelial cells. 15(S)-HETE is a potent mucosecretagogue in human airways. It is a metabolite of 15-lipoxygenase. 15(S)-HETE is an endogenous ligand for peroxisome proliferator-activated receptor γ (PPARγ).