Fenofibrate-d6
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Fenofibrate-d6 속성
- 녹는점
- 70-720C
- 저장 조건
- -20°C Freezer
- 용해도
- 클로로포름(약간 용해됨), 메탄올(적당)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- 흰색에서 황백색까지
- CAS 데이터베이스
- 1092484-56-4
Fenofibrate-d6 C화학적 특성, 용도, 생산
개요
Fenofibrate-d6 is intended for use as an internal standard for the quantification of fenofibrate by GC- or LC-MS. Fenofibrate is an agonist of peroxisome proliferator-activated receptor α (PPARα) with EC50 values of 18 and 30 μM for mouse and human receptors, respectively, in a transactivation assay. It is selective for PPARα over PPARγ (EC50s = 300 and 200 μM for mouse and human receptors, respectively) and lacks activity at mouse and human PPARδ at a concentration of 100 μM. In vivo, fenofibrate (50-100 mg/kg) reduces plasma levels of triglycerides, C-reactive protein, and malondialdehyde (MDA) in mice with fructose-induced hypertriglycemia in a dose-dependent manner. It decreases glomerular and tubular atrophy and necrosis induced by cisplatin in rat kidney when administered at a dose of 100 mg/kg. Fenofibrate also reduces the number of pulmonary lesions induced by 4-nitroquinoline 1-oxide (4-NQO) in lung of Tsumura Suzuki obese diabetic (TSOD) mice.화학적 성질
White Solid용도
Antilipemic. It is a lipid regulating drug. Increases high density lipoprotein levels by reducing cholesteryl ester transfer protein expresion.Fenofibrate-d6 준비 용품 및 원자재
원자재
준비 용품
Fenofibrate-d6 공급 업체
글로벌( 30)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| SIMSON PHARMA LIMITED | +91-8291074273 |
k.das@simsonpharma.com | India | 228 | 58 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 |
shchemsky@sina.com | China | 32344 | 50 |
| Cato Research Chemicals Inc. | 020-81960175 |
min.he@cato-chem.com | China | 1958 | 55 |
| Artis Biotech Co. Ltd. | 19138486554 18582380095 |
sales@artisbio.com | China | 3066 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 |
info@efebio.com | China | 9709 | 58 |
| Nanjing Haolv Biotechnology Co.,Ltd | 025-84622273 02584622273; |
kexin.zhou@haolvbiotech.com | China | 3021 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 |
sales@chemegen.com | China | 11289 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 |
rose.shi@synzest.com | China | 9287 | 58 |
| Hubei Xinyang Medical Technology Co., Ltd | 15347293736 15347293736 |
2853117764@qq.com | China | 8870 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 |
marketing1@energy-chemical.com | China | 44894 | 58 |