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2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE

2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE 구조식 이미지

카스 번호:: 194085-75-1

상품명:: 2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE

동의어(영문):: YKP 509;RWJ 333369;Carisbamate;JNJ 10234094;(S)-Carisbamate;CarisbaMate (RWJ-333369);2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE;[(2S)-2-(2-chlorophenyl)-2-hydroxyethyl] carbamate;1,2-ETHANEDIOL,1-(2-CHLOROPHENYL)-, 2-CARBAMATE, (S)-;1,2-Ethanediol,1-(2-chlorophenyl)-, 2-carbaMate, (1S)-

CBNumber:: CB11474577

분자식:: C813CH8D2Cl15NO3

포뮬러 무게:: 215.63

MOL 파일:: 194085-75-1.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 28

2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE 속성

녹는점: 131-132°C

저장 조건: Refrigerator

용해도: DMSO(약간 용해됨), 메탄올(약간 용해됨)

물리적 상태: 고체

물리적 상태: 단단한 모양

색상: 흰색에서 황백색까지

안전

2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE C화학적 특성, 용도, 생산

개요

Carisbamate is an antiepileptic agent., In vivo, administration of carisbamate (10-60 mg/kg) dose-dependently reduces spike and wave discharges in the frontoparietal cortex in a rat model of absence seizures. Carisbamate (10 mg/kg) increases latency to the first running episode in the Wistar audiogenic sensitive rat model of convulsive seizures. It also reduces motor seizure frequency in a rat model of spontaneous seizures in a dose-dependent manner. Carisbamate blocks Na_v1.2 channels (IC₅₀ = 68 μM for rat channels) and inhibits repetitive firing of action potentials in rat hippocampal neurons in a dose-dependent manner. It also reduces T-type Ca²⁺ currents in HEK cells transfected with human recombinant Ca_v3.1 channels at a concentration of 300 μM.

용도

Carisbamate is being developed for adjuvant treatment of partial onset epilepsy. Carisbamate produces anticonvulsant effects in primary generalized, complex partial and absence-type seizure models, an d exhibits neuroprotective and antiepileptogenic properties in rodent epilepsy models.

2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE 준비 용품 및 원자재

원자재

준비 용품

2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE 공급 업체

글로벌( 28)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	7019	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
AFINE CHEMICALS LIMITED	0571-85134551	info@afinechem.com	CHINA	15377	58
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3136	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
GIHI CHEMICALS CO.,LIMITED	+8618058761490	info@gihichemicals.com	China	50000	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	Mandy@hangyubiotech.com	China	11013	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32344	50