4-METHOXYCINNAMIC ACID
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4-METHOXYCINNAMIC ACID 속성
- 녹는점
- 173.5 °C(lit.)
- 끓는 점
- 342.6±17.0 °C(Predicted)
- 밀도
- 1.195±0.06 g/cm3(Predicted)
- 저장 조건
- Keep in dark place,Sealed in dry,Room Temperature
- 용해도
- 에탄올, 에틸 아세테이트 및 기타 유기 용매에 용해됩니다.
- 산도 계수 (pKa)
- 4.60±0.10(Predicted)
- 물리적 상태
- powder to crystal
- 색상
- 흰색에서 거의 흰색
- BRN
- 510468
- InChIKey
- AFDXODALSZRGIH-QPJJXVBHSA-N
- LogP
- 1.264 (est)
- CAS 데이터베이스
- 943-89-5(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 36/37/38 | ||
| 안전지침서 | 26-37/39 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | UD3391300 | ||
| F 고인화성물질 | 8 | ||
| TSCA | Yes | ||
| HS 번호 | 2918.29.7500 | ||
| 위험 등급 | IRRITANT |
4-METHOXYCINNAMIC ACID C화학적 특성, 용도, 생산
용도
Esters derived from trans-4-methoxycinnamic acid are effective absorbers of UV radiation. The starting material was trans-4-methoxycinnamic acid and 3,5dimethoxybenzoic acid methyl ester in isolated avenanthramide alkaloids synthsis. trans-4-Methoxycinnamic acid was converted into its acid chloride (yield 98%) with thionyl chloride. Employed in organic synthesis of pharmaceutical intermediates, synthetic anti-adrenergic drugs esmolol, cosmetics ultraviolet absorption.제조 방법
4-methoxycinnamic acid synthesis : In a 25-mL, roundbottomed flask, 4-methoxybenzaldehyde (0.804 mL, 6.61 mmol) (3), malonic acid (1.75 g, 16.8 mmol), and β-alanine (0.10 g, 1.12 mmol) were dissolved in pyridine (3.0 mL, 37.1 mmol) and heated under reflux for 90 minutes. After cooling to room temperature, the reaction mixture was placed in an ice bath and 8.0 mL of concentrated HCl was slowly added. The resulting white precipitate was collected by vacuum filtration, washed with cold water (2 x 10mL) and dried thoroughly. The product was recrystallized from absolute ethanol (~20 mL).
Synthesis of 4-methoxycinnamic acid
Purification Methods
Crystallise the acid from MeOH to constant melting point and UV spectrum. [Beilstein 10 IV 1005.]4-METHOXYCINNAMIC ACID 준비 용품 및 원자재
원자재
2-Propen-1-one, 1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)-, (2E)-
4-METHOXYCINNAMYLALCOHOL
TRANS-2-(4-METHOXYPHENYL)-
4-METHOXYBENZENEDIAZONIUM TETRAFLUOROBORATE
4-Methoxystyrene
다이에틸아민
아니스알데히드
carbon monoxide
이산화탄소
4-아이오딘아니솔
준비 용품
4-METHOXYCINNAMIC ACID 공급 업체
글로벌( 201)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Dalian Richfortune Chemicals Co., Ltd | 0411-84820922 8613904096939 |
sales@richfortunechem.com | China | 303 | 57 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 |
sales@chemdad.com | China | 39916 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | 18192627656 |
1012@dideu.com | China | 3422 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 |
info@dycnchem.com | CHINA | 52867 | 58 |
| CR Corporation Lomited | |
fred.wen@crcorporation.cn | CHINA | 12069 | 58 |