Omarigliptin (MK-3102)
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Omarigliptin (MK-3102) 속성
- 끓는 점
- 529.4±60.0 °C(Predicted)
- 밀도
- 1.61±0.1 g/cm3(Predicted)
- 저장 조건
- 2-8°C(protect from light)
- 용해도
- insoluble in EtOH; insoluble in H2O; ≥17.15 mg/mL in DMSO
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 9.11±0.60(Predicted)
- InChI
- InChI=1S/C17H20F2N4O3S/c1-27(24,25)23-7-10-6-22(8-16(10)21-23)12-5-15(20)17(26-9-12)13-4-11(18)2-3-14(13)19/h2-4,7,12,15,17H,5-6,8-9,20H2,1H3/t12-,15+,17-/m1/s1
- InChIKey
- MKMPWKUAHLTIBJ-ISTRZQFTSA-N
- SMILES
- [C@H]1(C2=CC(F)=CC=C2F)OC[C@H](N2CC3=CN(S(C)(=O)=O)N=C3C2)C[C@@H]1N
- CAS 데이터베이스
- 1226781-44-7
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
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| 예방조치문구: |
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Omarigliptin (MK-3102) C화학적 특성, 용도, 생산
개요
Merck earned its first global approval for omarigliptin in Japan in 2015, and phase III development is ongoing in other countries around the globe for this interesting small molecule DPP-4 inhibitor. Interestingly, while most DPP-4 inhibitors used to treat type 2 DM require daily administration, omarigliptin is a weekly treatment. The process-scale synthesis of omarigliptin has been nicely described in an October 2015 paper from the Merck process group.용도
Omarigliptin is a potent and selective dipeptidyl peptidase 4 (DPP-4) inhibitor to be used as treatment for type 2 diabetes.Omarigliptin (MK-3102) 준비 용품 및 원자재
원자재
준비 용품
Omarigliptin (MK-3102) 공급 업체
글로벌( 241)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hangzhou ICH Biofarm Co., Ltd | +undefined8613073685410 |
sales@ichemie.com | China | 985 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 |
sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21689 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9344 | 55 |
| Shanghai Yingrui Biopharma Co., Ltd. | +86-21-33585366 - 03@ |
sales03@shyrchem.com | CHINA | 738 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32686 | 60 |
| Lianyungang happen teng technology co., LTD | 15950718863 |
wang666xt@163.com | CHINA | 295 | 58 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Biochempartner | 0086-13720134139 |
candy@biochempartner.com | CHINA | 967 | 58 |
Omarigliptin (MK-3102) 관련 검색:
tert-butyl [(2R,3S)-2-(2,5-difluorophenyl)-5-hydroxytetrahydro-2H-pyran-3-yl]carbaMate
MK-2206 2HCl
MK-4101
mk-1064
MK 0557
MK-5172
Mk-2461 .
(E)-3-[[[3-[2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-[[(3-DIMETHYLAMINO)-3-OXOPROPYL]THIO]METHYL]THIO]-PROPANOIC ACID, SODIUM SALT
OLANZAPINE N-OXIDE
5-[(2-Chloroethyl)(2-hydroxyethyl)aMino]-1-Methyl-1H-benziMidazole-2-butanoic Acid
10,11-dihydro-10,11-dihydroxy-5H-dibenzazepine-5-carboxamide
Olmesartan impurity 43
Olanzapine Related Compound B
Okasepine impurity 4
Olaparib Metabolite M12
Teneligliptin Hydrobromide
Saxagliptin
Alogliptin benzoate