PIK-294
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PIK-294 속성
- 끓는 점
- 790.4±70.0 °C(Predicted)
- 밀도
- 1.43
- 저장 조건
- -20°C
- 용해도
- ≥24.5 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
- 산도 계수 (pKa)
- 8.95±0.10(Predicted)
- 물리적 상태
- 가루
- 색상
- 흰색에서 베이지색
- CAS 데이터베이스
- 900185-02-6
PIK-294 C화학적 특성, 용도, 생산
용도
PIK-294 is a derivative of PIK-293 (P437700) and a highly selective inhibitor of p110δ which is an isoform of phosphoinositide 3-kinase (PI3K).Biochem/physiol Actions
PIK-294 is a highly selective inihibitor of the phosphoinositide 3-kinase (PI3K) p110δ with an IC50 value of 10 nM compared to IC50 values of 10 μM, 490 nM and 160 nM for PI3Kα/β/γ, respectively. PIK-294 has been used to help distinguish the unique roles of the various PI3-K isoforms. For example, in a study of CXCL8-induced neutrophil migration, PIK-294 inhibited both chemokinetic and chemotactic CXCL8-induced migration whereas PI3Kγ inhibitor AS-605240 markedly reduced CXCL8 induced chemokinetic migration but had no effect on CXCL8 induced chemotactic migration.PIK-294 준비 용품 및 원자재
원자재
준비 용품
PIK-294 공급 업체
글로벌( 104)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32836 | 60 |
Biochempartner | 0086-13720134139 |
candy@biochempartner.com | CHINA | 967 | 58 |
Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63711 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49392 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 |
1026@dideu.com | China | 24099 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 |
sales@sarms4muscle.com | China | 10522 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 |
sales@invivochem.cn | United States | 6393 | 58 |
LEAP CHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 24738 | 58 |
ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 |
trendseenbio@gmail.com | China | 11681 | 58 |
PIK-294 관련 검색:
PIK-93, 5 mg USP/EP/BP
PIK-90, 50 mg USP/EP/BP
PIK-75, Hydrochloride Salt USP/EP/BP
PIK-75 Hydrochloride
PIK-93
N-(2,3-Dihydro-7,8-dimethoxyimidazo[1,2-c]quinazolin-5-yl)-3-pyridinecarboxamide
PIK-293
WZ4003
Y27632 (hydrochloride)
42-(Dimethylphosphinate)rapamycin
HS-173
Bupropion hydrochloride
Clonidine hydrochloride