Gefitinib-d6
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Gefitinib-d6 속성
- 저장 조건
- Store at -20°C
- 용해도
- DMF: 20 mg/ml,DMSO: 20 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml,Ethanol: 0.3 mg/ml
- 물리적 상태
- 고체
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
Gefitinib-d6 C화학적 특성, 용도, 생산
개요
Gefitinib-d6 is intended for use as an internal standard for the quantification of gefitinib by GC- or LC-MS. Gefitinib is an EGFR inhibitor (IC50s = 0.023-0.079 μM). It inhibits colony formation of GEO colon, ZR-75-1 and MCF-10A breast, and OVCAR-3 ovarian cancer cell lines in soft agar assays (IC50s = 0.2-0.4 μM). Gefitinib (0.1 to 1 μM) induces apoptosis and inhibits EGFR autophosphorylation in the same cells. In vivo, gefitinib (1.25, 2.5, and 5 mg/kg) reduces tumor volume and increases survival in a GEO mouse xenograft model. Formulations containing gefitinib have been used in the treatment of non-small cell lung cancer (NSCLC).용도
Gefitinib-d6 is the labeled version of Gefitinib (G304000), which is an antineoplastic.Gefitinib-d6 준비 용품 및 원자재
원자재
준비 용품
Gefitinib-d6 공급 업체
글로벌( 15)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
S.Z. PhyStandard Bio-Tech. Co., Ltd. | 0755-4000505016 13380397412 |
3001272453@qq.com | China | 4975 | 50 |
Nanjing XiZe Biotechnology CO., Ltd. | 025-58362220 15250997978 |
1511893459@qq.com | China | 7715 | 55 |
Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 |
sales@rrkchem.com | China | 55827 | 58 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 |
sales@chemegen.com | China | 11289 | 58 |
Cato Research Chemicals Inc. | 020-81215950 4000-868-328 |
customer@uwalab.com | United States | 10413 | 58 |
Taizhou Nanfeng Pharmaceutical Research Institute | 12345678910 |
nanfengdrug@163.com | China | 15323 | 58 |
Shanghai YuZn Pharm. Technology Co.,Ltd. | 15921286451; 15921286451 |
2010681527@qq.com | China | 5072 | 58 |
Shanghai isotope chemical co.,ltd | 021-021-51600108 13062666369 |
sales@chinaisotope.com | China | 4272 | 58 |
Nanjing Tengyi Biotechnology Co., Ltd | 025-58851786 17714337195 |
sales@tybiochem.com | China | 4257 | 58 |
Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 |
customer_service@efebio.com | China | 8740 | 58 |
Gefitinib-d6 관련 검색:
4-(3-Chloropropyl)morpholine
4,4'-(propane-1,3-diyl)bismorpholine
Gefitinib N-Oxide
4-Defluoro-4-hydroxy Gefitinib
Gefitinib
3-Hydroxy-4-methoxybenzonitrile
3-Chloro-4-fluoroaniline
2-Amino-4-methoxy-5-(3-morpholinopropoxy)benzonitrile
7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one
2-aMino-4-Methoxy-5-(3-Morpholinopropoxy)benzaMide
6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one
3,4-Dichloroaniline
N-(3-chloro-4-fluorophenyl)-7 -methoxy-6-(3-morpholinopropoxy)-N-(3-morpholinopropyl)quinazolin-4-amine
Gefitinib 3,4-Difluoro Impurity HCl
6,7-Dimethoxy-3,4-dihydroquinazoline-4-one
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol
3-Deschloro-4-Desfluoro-4-Chloro-3-Fluorogefitinib
4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate