L-퓨코제

L-퓨코제
L-퓨코제 구조식 이미지
카스 번호:
2438-80-4
한글명:
L-퓨코제
동의어(한글):
L-퓨코제;L-퓨코제(L-FUCOSE)
상품명:
L-Fucose
동의어(영문):
L-(-)-FUCOSE;6-DEOXY-L-GALACTOSE;L-Galactose, 6-deoxy-;L-fucopyranose;(2S,3R,4R,5S)-2,3,4,5-tetrahydroxyhexanal;L-(-)-Fucose ,99%;6-DEOXY-BETA-GALACTOSE;Fuose;L-FUCOSE;L-FUCOSE
CBNumber:
CB1448036
분자식:
C6H12O5
포뮬러 무게:
164.16
MOL 파일:
2438-80-4.mol
MSDS 파일:
SDS

L-퓨코제 속성

녹는점
150-153 °C(lit.)
끓는 점
211.61°C (rough estimate)
알파
-73~-77°(D/20℃)(c=4,H2O,24hr)
밀도
1.1738 (rough estimate)
굴절률
-75.5 ° (C=10, H2O)
저장 조건
Inert atmosphere,Store in freezer, under -20°C
용해도
H2O: 0.1 g/mL, 투명, 무색
산도 계수 (pKa)
12.50±0.20(Predicted)
물리적 상태
가루
색상
베이지~연한 갈색~자주색~회색
수용성
물에 용해됩니다.
감도
Hygroscopic
Merck
14,4279
BRN
1723321
안정성
안정적인. 강한 산화제와 호환되지 않습니다.
InChIKey
SHZGCJCMOBCMKK-DLABPRKASA-N
LogP
-0.340 (est)
CAS 데이터베이스
2438-80-4(CAS DataBase Reference)
EPA
L-Galactose, 6-deoxy- (2438-80-4)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
안전지침서 24/25
WGK 독일 3
F 고인화성물질 3-10
TSCA Yes
HS 번호 29400090
기존화학 물질 KE-09588
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H302 삼키면 유해함 급성 독성 물질 - 경구 구분 4 경고 GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 피부에 자극을 일으킴 피부부식성 또는 자극성물질 구분 2 경고 GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 눈에 심한 자극을 일으킴 심한 눈 손상 또는 자극성 물질 구분 2A 경고 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 호흡 자극성을 일으킬 수 있음 특정 표적장기 독성 - 1회 노출;호흡기계 자극 구분 3 경고 GHS hazard pictograms
예방조치문구:
P261 분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P305+P351+P338 눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
NFPA 704
1
0 0

L-퓨코제 C화학적 특성, 용도, 생산

화학적 성질

White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents.

화학적 성질

l-fucose is a six-carbon sugar also known as 6-deoxy-l-galactose. Its molecular formula is C6H12O5 and its melting point is 150.0–153.0 °C. It is a white crystalline powder that easily absorbs moisture, and its hydrophilicity is weaker than that of other monosaccharides. l-fucose is the main form of fucose found in nature and is also the only levorotatory sugar used by mammals, while d-fucose is found only in some glycosides[1].

출처

L-Fucose exists in nature in various biological niches. A major natural source of L-fucose is the brown algal polysaccharide fucoidan. It is also present in the polysaccharides of tragacanth, potatoes, kiwi, soybeans, varieties of wing peas, canola and other plants.L-Fucose is a minor component in plant cell wall polysaccharides, specifically rhamnogalacturonan, xyloglucan and also arabinogalactan proteins that are involved in plant cell elongation.

용도

L-Fucose was isolated from seaweed. It finds application in cosmetics, pharmaceuticals and dietary supplements. It is used in the determination of antigen in A and B blood group. It is also used in the selection-mediated leukocyte-endothelial adhesion and host-microbe interactions. L-Fucose is also used in anti aging creams as well as to promote the accelerated healing of wounds and to reduce allergy.

정의

ChEBI: L-fucopyranose is the pyranose form of L-fucose. It has a role as an Escherichia coli metabolite and a mouse metabolite. It is a L-fucose and a fucopyranose.

화학 반응

L-Fucose is oxidised by the enzyme L-fucose dehydrogenase in the presence of nicotinamide-adenine dinucleotide phosphate (NADP+) to L-fucono-1,5-lactone with the formation of reduced nicotinamideadenine dinucleotide phosphate (NADPH) (1).
(L-fucose dehydrogenase) (1)
L-Fucose + NADP+ --> L-fucono-1,5-lactone + NADPH + H+
The amount of NADPH formed in this reaction is stoichiometric with the amount of L-fucose. It is the NADPH which is measured by the increase in absorbance at 340 nm.

생물학적 활성

L-Fucose (6-Deoxy-L-galactose) is used in studies of fucoidan polysaccharides containing glycans. It is studied as a glycan modifying carbohydrate that generates antigenic sites recognized by IgE antibodies. It is used as a substrate to identify, differentiate, and characterize enzymes such as fucosidase(s),l-fucose isomerase(s), and L-fucose dehydrogenase(s). It may be used to study organelles, and bacterial microcompartments, involved in the degradation of plant and algal cell wall sugars. L-Fucose may also be used as a reference compound in rare sugar identification and analysis.

L-퓨코제 준비 용품 및 원자재

원자재

준비 용품


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