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탄산나트륨, 모노수화물

탄산나트륨, 모노수화물
탄산나트륨, 모노수화물 구조식 이미지
카스 번호:
5968-11-6
한글명:
탄산나트륨, 모노수화물
동의어(한글):
나트륨탄산염,0.1노르말용액;탄산나트륨,모노수화물;탄산나트륨일수화물;탄산나트륨,모노수화물(SODIUMCARBONATE,MONOHYDRATE)
상품명:
SODIUM CARBONATE, MONOHYDRATE
동의어(영문):
SODA;NA2CO3;SODA ASH;SOLVAY SODA;Soda crystals;SOD.CARBONATE;ANHYDROUS SODA;DENSE SODA ASH;SODA ASH, DENSE;Lightand/ordense
CBNumber:
CB1704053
분자식:
CH2Na2O4
포뮬러 무게:
124
MOL 파일:
5968-11-6.mol

탄산나트륨, 모노수화물 속성

녹는점
851 °C(lit.)
끓는 점
1600 °C
밀도
2.53
저장 조건
Store at RT.
용해도
H2O: 1 M at 20 °C, clear, colorless
물리적 상태
Powder/Solid
Specific Gravity
2.25
색상
White
수용성
Soluble in water. Insoluble in alcoholSoluble in water and glycerol. Insoluble in alcohol, acetone, alkyl acetates,benzonitrile and liquid ammonia.
감도
Hygroscopic
Merck
14,8596
안정성
Stable. Incompatible with strong acids, aluminium, fluorine, lithium, phosphorus oxides.
CAS 데이터베이스
5968-11-6(CAS DataBase Reference)
EPA
Sodium carbonate, monohydrate (5968-11-6)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xi
위험 카페고리 넘버 36
안전지침서 26-22
WGK 독일 1
RTECS 번호 VZ4050000
F 고인화성물질 3
TSCA Yes
HS 번호 28362000
그림문자(GHS):
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H303 삼키면 유해할 수 있음 급성 독성 물질 - 경구 구분 5 P312
H319 눈에 심한 자극을 일으킴 심한 눈 손상 또는 자극성 물질 구분 2A 경고 P264, P280, P305+P351+P338,P337+P313P
H332 흡입하면 유해함 급성 독성 물질 흡입 구분 4 경고 P261, P271, P304+P340, P312
예방조치문구:
P261 분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P304+P340 흡입하면 신선한 공기가 있는 곳으로 옮기고 호흡하기 쉬운 자세로 안정을 취하시오.
P305+P351+P338 눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
P337+P313 눈에 대한 자극이 지속되면 의학적인 조치· 조언를 구하시오.
NFPA 704
0
2 0

탄산나트륨, 모노수화물 C화학적 특성, 용도, 생산

화학적 성질

white powder

화학적 성질

Sodium carbonate is a white, almost white, or colorless inorganic salt, produced as crystalline powder or granules. It is hygroscopic and odorless with an alkaline taste.

용도

Buffers; pH adjustment.

생산 방법

Sodium carbonate is produced by the ammonia-soda process, also known as the Solvay process.

Pharmaceutical Applications

Sodium carbonate is used as an alkalizing agent in injectable, ophthalmic, oral, and rectal formulations. In effervescent tablets or granules, sodium carbonate is used in combination with an acid, typically citric acid or tartaric acid. When the tablets or granules come into contact with water, an acid– base reaction occurs in which carbon dioxide gas is produced and the product disintegrates. Raw materials with low moisture contents are required to prevent the early triggering of the effervescent reaction.
As an alkalizing agent, concentrations of sodium carbonate between 2% and 5% w/w are used in compressed tablet formulations. As an effervescent agent, concentrations of sodium carbonate up to 10% w/w can be used.
Therapeutically, sodium carbonate is also used as an oral antacid.

공업 용도

The most prominent characteristic of soda ash in solution is the high buffered pH response. For example, changing the sodium carbonate dosage from 0.03% to 30% only causes the solution pH to change from 10.5 to 11.7. Because of this, in mineral processing application, soda ash is used for pH control to a maximum value of 10.5.

공업 용도

Soda ash is the name of various grades of sodium carbonate (Na2CO3). A large portion of soda ash is manufactured via the Solvay process, based on the following reaction:
NH3 + CO2 + H2O → NH4HCO3
NaCl + NH4HCO3→ NaHCO3 + NH4Cl
2NaHCO3 + heat → Na2CO3 + CO2 (recycled)
Soda ash is an off-white to white anhydrous powder or granular material. The quality of soda ash is usually characterized by the percent of sodium oxide (Na2O) content.

Safety

Sodium carbonate is used in injectable, oral, and rectal pharmaceutical formulations. The pure form of sodium carbonate is mildly toxic by ingestion, moderately toxic by inhalation and SC routes, and very toxic by the IP route. It is irritating to the skin and eyes. Dust and vapors of sodium carbonate may irritate mucous membranes, causing coughing and shortness of breath. It also has experimental reproductive effects.
Sodium carbonate can migrate to food from packaging materials. When used as an excipient or antacid, sodium carbonate is generally regarded as a nontoxic and nonirritating material.
LD50 (mouse, IP): 0.12 g/kg
LD50 (mouse, SC): 2.21 g/kg
LD50 (rat, oral): 4.09 g/kg

저장

Sodium carbonate converts to the monohydrate form when in contact with water and produces heat. It begins to lose carbon dioxide at temperatures above 400℃ and decomposes before boiling. Store in airtight containers.

비 호환성

Sodium carbonate decomposes when in contact with acids in the presence of water to produce carbon dioxide and effervescence. It may react violently with aluminum, phosphorous pentoxide, sulfuric acid, fluorine, and lithium.

Regulatory Status

GRAS listed. Accepted for use as a food additive in Europe. Included in the FDA Inactive Ingredients Database (injections; ophthalmic solution; oral capsules and tablets; rectal suspensions). Included in the Canadian List of Acceptable Non-medicinal Ingredients. Included in parenteral (powder for solution for injection) and nonparenteral medicines (oral effervescent tablets, soluble tablets, granules, lozenges, chewing gums) licensed in the UK.
USP32–NF27 allows either the anhydrous or the monohydrate form.

탄산나트륨, 모노수화물 준비 용품 및 원자재

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