AMINO ACID HYDROXAMATES DL-SERINE HYDROXAMATE

AMINO ACID HYDROXAMATES DL-SERINE HYDROXAMATE 구조식 이미지
카스 번호:
55779-32-3
상품명:
AMINO ACID HYDROXAMATES DL-SERINE HYDROXAMATE
동의어(영문):
SHX;dl-serine hydroxamate;Propanamide, 2-amino-N,3-dihydroxy-;DL-SERINE HYDROXAMATE, SERYL-TRNA SY;(Z)-2-aMino-N,3-dihydroxypropaniMidic acid;AMINO ACID HYDROXAMATES DL-SERINE HYDROXAMATE;rac-(R*)-2-Amino-3-hydroxypropanehydroxamic acid;DL-Serine hydroxaMate seryl-tRNA synthetase inhibitor
CBNumber:
CB2281528
분자식:
C3H8N2O3
포뮬러 무게:
120.11
MOL 파일:
55779-32-3.mol
MSDS 파일:
SDS

AMINO ACID HYDROXAMATES DL-SERINE HYDROXAMATE 속성

저장 조건
-20°C

안전

WGK 독일 3

AMINO ACID HYDROXAMATES DL-SERINE HYDROXAMATE C화학적 특성, 용도, 생산

용도

Serine has been used as an inhibitor of seryl-tRNA synthetase. DL-Serine hydroxamate is used to induce metabolic synthesis of guanosine 3′-diphosphate 5′-diphosphate (ppGpp) in E. coli by amino acid starvation. It is also used to synchronize cell cycle in E. coli cultures by inhibition of tRNA charging.

Biochem/physiol Actions

Serine is involved in the one-carbon unit metabolism. It is associated with the biosynthesis of cysteine, ceramide, phosphatidylserine, purine and pyrimidine. In bacteria, it participates in tryptophan synthesis. Gluconeogenesis, one of the important biochemical processes, involves serine, particularly in ruminants. Protein phosphorylation is one such event that utilizes serine. Glycine, a metabolic product of serine, serves as an antioxidant and a neurotransmitter. D-serine is known to activate the N-methyl-D-aspartate (NMDA) receptors of the brain. Serine hydroxamate, a structural analogue of serine prevents seryl-tRNA (transfer ribonucleic acid) charging and thereby decreases phospholipid and nucleic acid synthesis in Escherichia coli.

AMINO ACID HYDROXAMATES DL-SERINE HYDROXAMATE 준비 용품 및 원자재

원자재

준비 용품


AMINO ACID HYDROXAMATES DL-SERINE HYDROXAMATE 공급 업체

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CONIER CHEM AND PHARMA LIMITED
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Syntechem Co.,Ltd
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Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969
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