Anti-Tau antibody, Mouse monoclonal

Anti-Tau antibody, Mouse monoclonal 구조식 이미지
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상품명:
Anti-Tau antibody, Mouse monoclonal
동의어(영문):
Anti-Tau antibody, Mouse monoclonal
CBNumber:
CB24669746
분자식:
포뮬러 무게:
0
MOL 파일:
Mol file

Anti-Tau antibody, Mouse monoclonal 속성

저장 조건
-20°C
물리적 상태
완충 수용액

안전

Anti-Tau antibody, Mouse monoclonal C화학적 특성, 용도, 생산

용도

Anti-tau antibody, mouse monoclonal may be used in immunoblotting and immunoprecipitation.

일반 설명

Anti-tau antibody, mouse monoclonal (mouse IgG1 isotype) is derived from the tu53 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB /C mice. Tau, also known as microtubule-associated protein tau (MAPT), belongs to microtubule-associated proteins (MAP) family. It consists of six isoforms in the neurons of the adult human brain. MAPT gene is located on the human chromosome at 17q21.31.

Biochem/physiol Actions

Tau loses its microtubule-binding activity and aggregates into paired helical filaments (PHFs) during neurodegenerative disorders. It can undergo modifications such as hyperphosphorylation, nonenzymatic glycosylation and acetylation, which result in the generation of aberrant aggregates such as found in neurofibrillary tangles (NFTs) in Alzheimer′s disease. It is present abundantly in intraneuronal and glial fibrillar lesions formed during neurodegenerative disorders such as tauopathies and Alzheimer′s disease.

Anti-Tau antibody, Mouse monoclonal 준비 용품 및 원자재

원자재

준비 용품


Anti-Tau antibody, Mouse monoclonal 공급 업체

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