포스미도마이신
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포스미도마이신 속성
- 녹는점
- 158-160° (dec); mp 160-166° (dec) (Hemmi)
- 저장 조건
- -20°C
- 용해도
- H2O: 용해성20mg/mL, 투명
- 물리적 상태
- 가루
- 색상
- 흰색에서 베이지색
안전
WGK 독일 | 3 | ||
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독성 | LD50 in mice and rats (mg/kg): >11000 orally; ~8000 s.c. (Wiesner, 2003) |
포스미도마이신 C화학적 특성, 용도, 생산
용도
Fosmidomycin sodium salt hydrate has been used as an inhibitor of 1-deoxy-D-xylulose 5-phosphate reductoisomerase in a study to determine monotropin carvacrol biosynthesis in Satureja khuzistanica plant.정의
ChEBI: Propylphosphonic acid in which one of the hydrogens at position 3 is substituted by a formyl(hydroxy)amino group. An antibiotic obtained from Streptomyces lavendulae, it specifically inhibits DXP reductoisomerase (EC 1.1.1.267), a key enzyme i the non-mevalonate pathway of isoprenoid biosynthesis.Biochem/physiol Actions
Fosmidomycin is an inhibitor of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) (MEP synthase): an antimalarial compound. 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) is an enzyme involved in the first step in the nonmevalonate pathway for isoprenoid biosynthesis in Gram-negative, Gram-positive bacteria, plants, and the parasite causing the most virulent form of malaria, Plasmodium falciparum (Mammals produce isoprenoids via the mevalonate pathway).포스미도마이신 준비 용품 및 원자재
원자재
준비 용품
포스미도마이신 공급 업체
글로벌( 5)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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BOC Sciences | 1-631-485-4226; 16314854226 |
info@bocsci.com | United States | 14059 | 65 |
Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 |
isunpharm@qq.com | China | 4428 | 55 |
Suzhou Vosun Biotech Co.,Ltd | 0512-66569378-8002 66569378 |
info@vosunchemical.com | China | 720 | 58 |
Changzhou Bojia Biomedical Technology Co., Ltd. | 2122619822 |
czbjpharma@126.com | China | 18488 | 58 |