HIF-1알파/2알파억제제

HIF-1알파/2알파억제제
HIF-1알파/2알파억제제 구조식 이미지
카스 번호:
329932-55-0
한글명:
HIF-1알파/2알파억제제
동의어(한글):
HIF-1알파/2알파억제제
상품명:
HIF-1alpha/2alpha Inhibitor
동의어(영문):
FM19G11;FM 19G11 NEW;FM19G11 >=98% (HPLC);HIF-1alpha/2alpha Inhibitor;HIF-1α/2α Inhibitor IV, FM19G11;2-Oxo-2-(p-tolyl)ethyl 3-(2,4-dinitrobenzamido)benzoate;[2-oxo-2-(p-tolyl)ethyl] 3-[(2,4-dinitrobenzoyl)amino]benzoate;3-[(2,4-Dinitrobenzoyl)amino]-benzoic acid 2-(4-methylphenyl)-2-oxoethyl ester;Benzoic acid, 3-[(2,4-dinitrobenzoyl)amino]-, 2-(4-methylphenyl)-2-oxoethyl ester
CBNumber:
CB32668403
분자식:
C23H17N3O8
포뮬러 무게:
463.4
MOL 파일:
329932-55-0.mol
MSDS 파일:
SDS

HIF-1알파/2알파억제제 속성

저장 조건
2-8°C
용해도
DMSO: ≥40mg/mL
물리적 상태
가루
색상
황백색부터 연한 갈색까지

안전

WGK 독일 3

HIF-1알파/2알파억제제 C화학적 특성, 용도, 생산

용도

FM19G11 has been used as ahypoxia-inducible factor-1α (HIF- 1α):
  • to study the effects ofFM19G11-loaded gold nanoparticles (NPs) on self-renewal and proliferation of ependymal stem progenitor cells (epSPCs) of mice
  • to study its effects on the O6-methylguanine DNA-methyltransferase (MGMT) expression in glioblastoma (GBM) cells
  • to study its effects on microphthalmia-associated transcription factor (MITF) expression in melanoma cell line

Biochem/physiol Actions

FM19G11 is an inhibitor of Hypoxia Inducible Factors α (HIFα), reported to affect self-renewal and differentiation of stem cells. Hypoxia-inducible factors (HIFs) are transcription factors that respond to changes in available oxygen in the cellular environment. Among other functions (like angiogenesis), HIFα proteins affect the self-renewal and the differentiation processes of stem cells. FM19G11 inhibits the HIFα proteins that repress the target genes of the two α subunits, in various tumor cell lines as well as in adult and embryonic stem cell (ESC) models.

HIF-1알파/2알파억제제 준비 용품 및 원자재

원자재

준비 용품


HIF-1알파/2알파억제제 공급 업체

글로벌( 30)공급 업체
공급자 전화 이메일 국가 제품 수 이점
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32836 60
Career Henan Chemica Co
+86-0371-86658258 +8613203830695
laboratory@coreychem.com China 30250 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 57511 58
AdooQ BioScience, LLC +1 (866) 930-6790
info@adooq.com United States 2784 58
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
info@efebio.com China 9707 58
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720
klq@cw-bio.com China 4182 55
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136
info@SuperLan-chem.com China 9943 58
Shanghai SuperLan Chemcial Technique Centre 021-2022843681 15618226720
chaolaichem@foxmail.com China 9082 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774
sales@glpbio.cn China 6870 58

Copyright 2019 © ChemicalBook. All rights reserved