Saccharocarcin B

Saccharocarcin B 구조식 이미지
카스 번호:
158475-33-3
상품명:
Saccharocarcin B
동의어(영문):
Saccharocarcin B;18H-16a,19-Metheno-16aH-benzo[b]naphth[2,1-j]oxacyclotetradecin-18,20(1H)-dione, 10-[[4-(acetylamino)-2,4,6-trideoxy-3-C-methylhexopyranosyl]oxy]-4-[[O-2,6-dideoxyhexopyranosyl-(1→4)-O-2,6-dideoxy-3-O-(tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)hexopyranosyl-(1→4)-2,6-dideoxyhexopyranosyl]oxy]-2,3,...
CBNumber:
CB32703762
분자식:
C68H103NO20
포뮬러 무게:
1254.54012
MOL 파일:
158475-33-3.mol

Saccharocarcin B 속성

밀도
1.29±0.1 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
물리적 상태
고체
산도 계수 (pKa)
4.50±1.00(Predicted)

안전

Saccharocarcin B C화학적 특성, 용도, 생산

용도

Saccharocarcin B is an unusual tetronic acid structurally related to kijanimicin, chlorothricin, tetrocarcins and versipelostatin, which has pronounced activity against Gram positive bacteria and Chlamydia trachomatis. Limited availability has restricted further investigation of this metabolite, however several members of this class have received considerable literature focus. Versipelostatin inhibits transcription from the promoter of GRP78, a gene that is activated as part of a stress signalling pathway under glucose deprivation resulting in unfolded protein response (UPR), causing death of glucose-deprived cells. Tetrocarcin A appears to target the phosphatidylinositide-3'-kinase/Akt signalling pathway.

Saccharocarcin B 준비 용품 및 원자재

원자재

준비 용품


Saccharocarcin B 공급 업체

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