C-Peptide EIA Kit

C-Peptide EIA Kit 구조식 이미지
카스 번호:
상품명:
C-Peptide EIA Kit
동의어(영문):
C-Peptide EIA Kit
CBNumber:
CB32892019
분자식:
포뮬러 무게:
0
MOL 파일:
Mol file

C-Peptide EIA Kit 속성

저장 조건
-20°C
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
유엔번호(UN No.) UN 3264 8 / PGIII
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H290 금속을 부식시킬 수 있음 금속 부식성물질 구분 1 경고 GHS hazard pictograms P234, P390, P404
예방조치문구:
P234 원래의 용기에만 보관하시오.
P390 물질손상을 방지하기 위해 누출물을 흡수시키시오.

C-Peptide EIA Kit C화학적 특성, 용도, 생산

용도

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

일반 설명

The C-Peptide Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting C-Peptide peptide based on the principle of Competitive Enzyme Immunoassay. EIA-CPE-1 only detects C-peptide, not Insulin A or B chain.

Biochem/physiol Actions

C-peptide inhibits endothelial dysfunction under high glucose conditions via inhibition of nuclear factor-κB (NF-κB) pathway. Experimental studies suggest that prolonged dosage of physiological concentration of C-peptide to type 1 diabetes patients minimizes diabetes-induced complications, such as glomerular hypertrophy and mesangial matrix expansion by interrupting transforming growth factor β1 (TGF-β1) and tumor necrosis factor α (TNFα) signaling pathway. C-peptide reduces diabetes-induced glomerular hyperfiltration by contraction of the afferent arteriole, dilation of the efferent arteriole, and by inhibition of tubular reabsorption. C-Peptide also plays a crucial role in renal pathophysiology. C-peptide binds to a cell surface receptor that is likely to be G-protein coupled. This interaction stimulates various cellular functions such as increasing intracellular Ca2+ concentration, enhancing PI3-K (phosphoinositide 3-kinase) activity, increased endothelial nitric oxide synthase (eNOS) transcription, and activation of the Na+/K+ ATPase and mitogen-activated protein kinase (MAPK) signaling pathway.

C-Peptide EIA Kit 준비 용품 및 원자재

원자재

준비 용품


C-Peptide EIA Kit 공급 업체

글로벌( 2)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80

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