Ogerin
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Ogerin 속성
- 저장 조건
- 2-8°C
- 용해도
- DMSO: 50 mg/ml
- 물리적 상태
- 가루
- 색상
- 흰색에서 베이지색
안전
Ogerin C화학적 특성, 용도, 생산
용도
Ogerin is a potent GPR68 modulator.Biochem/physiol Actions
Ogerin is a selective positive allosteric modulator of an orphan GPCR, GPR68, also known as Ovarian cancer G-protein coupled receptor 1 (OGR1). GPR68 is one of the proton or pH-sensing GPCRs that sense extracellular H(+). Ogerin potently potentiated proton-mediated GPR68-Gs signaling. Ogerin was not active in GPR68 knockout mice, but was found to suppress recall in fear conditioning in wild-type mice, showing an unexpected effect of GPR68 on learning and memory.효소 저해제
This GPR68 activator (FW = 307.35 g/mol; CAS 1309198-71-7), also named 2-[4-amino-6-[(phenylmethyl)amino]-1,3,5-triazin-2-yl]benzenemethanol, selectively and allosterically targets G-Protein-coupled Receptor 68, one of at least 120 non-olfactory G-protein-coupled receptors in the human genome that remain 'orphans' (i.e., they are pharmacologically dark, with no known endogenous ligands). Ogerin suppresses recall in fear conditioning in wild-type, but not in GPR68-knockout mice. GPR68 is also a newly recognized metastasis suppressor gene in certain cancers.Ogerin 준비 용품 및 원자재
원자재
준비 용품
Ogerin 공급 업체
글로벌( 18)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 52927 | 58 |
Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51471 | 80 |
BOC Sciences | -- |
info@bocsci.com | USA | 0 | 65 |
DC Chemicals | 021-58447131 13564518121 |
sales@dcchemicals.com | China | 9412 | 58 |
Shanghai hongqu biomedical technology co. LTD | 88888888888 |
hongquchem@qq.com | China | 5132 | 58 |
Energy Chemical | 021-58432009 400-005-6266 |
marketing@energy-chemical.com | China | 44941 | 58 |
Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; |
psaitong@jm-bio.com | China | 29778 | 58 |
TargetMol Chemicals Inc. | 4008200310 |
marketing@tsbiochem.com | China | 18779 | 58 |
Suzhou Zhixin Biotechnology Co., Ltd. | 0512-65118909 15162312715 |
sales@szzxbio.com | China | 2997 | 58 |