Ravuconazole
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Ravuconazole 속성
- 녹는점
- 64-66°C
- 알파
- D24 -29.1° (c = 1.03 in methanol)
- 끓는 점
- 674.9±65.0 °C(Predicted)
- 밀도
- 1.38±0.1 g/cm3(Predicted)
- 저장 조건
- -20°C Freezer
- 용해도
- DMF: 25 mg/ml; DMF:PBS (pH 7.2) (1:4): 0.25 mg/ml; DMSO: 20 mg/ml; Ethanol: 5 mg/ml
- 물리적 상태
- 결정성 고체
- 산도 계수 (pKa)
- 11.62±0.29(Predicted)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
Ravuconazole C화학적 특성, 용도, 생산
개요
Ravuconazole is an orally available triazole fungicide that potently inhibits the growth of a wide range of fungi (MICs range from 25 to 780 ng/ml). Like other azoles, ravuconazole inhibits cytochrome P450 (CYP) isoforms that are involved in ergosterol biosynthesis, interfering with the generation of the fungal and protozoan cell membranes. Ravuconazole specifically inhibits sterol 14α-demethylase (CYP51). As this enzyme is also important in the development of trypanosomes, ravuconazole is effective against T. cruzi infections in animal models of Chagas disease.화학적 성질
Off-White Solid용도
Ergosterol biosynthesis inhibitor. Antifungal.Ravuconazole 준비 용품 및 원자재
원자재
(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)butanethioaMide
(αS,βR)-β-(2,4-Difluorophenyl)-β-hydroxy-α-Methyl-1H-1,2,4-triazole-1-butanenitrile
2-Chloro-2',4'-difluoroacetophenone
4-(2-Bromoacetyl)benzonitrile
(2R,3R)-3-(2,4-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyraMide
3-chloro-2-(2,4-difluorophenyl)-2-(trimethylsilanyloxy)propionaldehyde
(S)-3-chloro-2-(2,4-difluorophenyl)-2-((trimethylsilyl)oxy)propanenitrile
4-Acetylbenzonitrile
준비 용품
Ravuconazole 공급 업체
글로벌( 97)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Biochempartner | 0086-13720134139 |
candy@biochempartner.com | CHINA | 967 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; |
factory@coreychem.com | China | 29826 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 |
sales@hzclap.com | CHINA | 6313 | 58 |
| Qiuxian Baitai New Material Co., LTD | +8618330912755 |
sale2@hbyalin.com | China | 1677 | 58 |
| AFINE CHEMICALS LIMITED | 0571-85134551 |
info@afinechem.com | CHINA | 15377 | 58 |
| Shenzhen Shengda Pharma Limited | 755-85269922 +8613424394241 |
sales@shengdapharm.com | CHINA | 310 | 58 |
| Guangzhou TongYi biochemistry technology Co.,LTD | +8613073028829 |
mack@tongyon.com | China | 2996 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 |
sales@invivochem.cn | United States | 6393 | 58 |
| Hebei Duling International Trade Co. LTD | +8618032673083 |
sales05@hbduling.cn | China | 15744 | 58 |