ANTIBIOTIC UCN-02

ANTIBIOTIC UCN-02 구조식 이미지
카스 번호:
121569-61-7
상품명:
ANTIBIOTIC UCN-02
동의어(영문):
UCN-02;UCN02,UCN 02;ANTIBIOTIC UCN-02;9,13-Epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one, 2,3,10,11,12,13-hexahydro-3-hydroxy-10-methoxy-9-methyl-11-(methylamino)-, (3S,9S,10R,11R,13R)-
CBNumber:
CB42446750
분자식:
C28H26N4O4
포뮬러 무게:
482.53
MOL 파일:
121569-61-7.mol

ANTIBIOTIC UCN-02 속성

끓는 점
705.7±60.0 °C(Predicted)
밀도
1.63±0.1 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
DMSO에 용해됨
물리적 상태
solution in ethanol.
산도 계수 (pKa)
12.25±0.70(Predicted)
안전
  • 위험 및 안전 성명
그림문자(GHS): GHS hazard pictograms
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
예방조치문구:
NFPA 704
3
0 0

ANTIBIOTIC UCN-02 C화학적 특성, 용도, 생산

개요

UCN-02 is a derivative of staurosporine and a stereoisomer of UCN-01 first isolated from a high staurosporine-producing Streptomyces culture as a minor co-metabolite. UCN-02 inhibits protein kinase C with a slightly reduced potency than UCN-01 (IC50 = 62 and 4.1 nM, for UNC-02 and UCN-01, respectively) and is cytotoxic to the growth of HeLa S3 cells.

용도

UCN-02 is an indolocarbazole isolated from a high staurosporine-producing Streptomyces culture as a minor co-metabolite. Although less selective than its isomer UCN-01, UCN-02 exhibits comparable activity and probably acts by similar mechanisms.

ANTIBIOTIC UCN-02 준비 용품 및 원자재

원자재

준비 용품


ANTIBIOTIC UCN-02 공급 업체

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