PIMARIC ACID

PIMARIC ACID 구조식 이미지
카스 번호:
127-27-5
상품명:
PIMARIC ACID
동의어(영문):
Pimaric;NSC 2956;PIMARIC ACID;Pimaric Acid (>DextropiMaric Acid;Δ8(14)-PiMaric Acid;Pimaric acid (PiMA);Pimaric Acid (> 75%);Hexazinone Impurity 27;8(14),15-PiMaradien-18-oic Acid
CBNumber:
CB4506393
분자식:
C20H30O2
포뮬러 무게:
302.45
MOL 파일:
127-27-5.mol

PIMARIC ACID 속성

녹는점
217-219°
알파
D18 +74.7° (c = 0.4 in chloroform); D20 +87.3° (in chloroform)
끓는 점
bp18 282°
밀도
1.0434 (rough estimate)
굴절률
1.4800 (estimate)
저장 조건
Store at -20°C
용해도
DMSO: soluble,Water: soluble
산도 계수 (pKa)
4.68±0.60(Predicted)
물리적 상태
Solid
색상
White to off-white
LogP
6.731 (est)
EPA
Pimaric acid (127-27-5)

안전

PIMARIC ACID C화학적 특성, 용도, 생산

개요

Pimaric acid is a resin acid that has been found in A. cordata and various pines. It reduces mRNA expression, protein levels, and promoter activity of matrix metalloproteinase-9 (MMP-9) in TNF-α-stimulated human aortic smooth muscle cells (HASMCs) in a concentration-dependent manner when used at concentrations ranging from 5 to 20 μM. Pimaric acid (10-20 μM) reduces nuclear expression and binding of the transcription factors NF-κB and AP-1 to the MMP-9 promoter in HASMCs. Pimaric acid also reduces TNF-α-induced HASMC migration to control levels when used at a concentration of 20 μg/ml.

용도

A novel activators of large-conductance Ca2+-activated K+ channel α-subunit.

PIMARIC ACID 준비 용품 및 원자재

원자재

준비 용품


PIMARIC ACID 공급 업체

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Amadis Chemical Company Limited
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