1-GLYCERYL N-[7-CHLORO-4-QUINOLYL]ANTHRANILATE HYDROCHLORIDE
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1-GLYCERYL N-[7-CHLORO-4-QUINOLYL]ANTHRANILATE HYDROCHLORIDE 속성
- 녹는점
- 170℃
- 끓는 점
- 618℃
- 밀도
- 1.428
- 굴절률
- 1.6800 (estimate)
- 인화점
- 328℃
- 저장 조건
- 2-8°C(protect from light)
- 용해도
- DMSO:100.0(Max Conc. mg/mL);268.24(Max Conc. mM)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- pKa (20°C) 7.2
- 수용성
- 38.46g/L(온도 미표시)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 22 | ||
| 안전지침서 | 36 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | CB2687000 | ||
| 독성 | LD50 orally in mice: >2 g/kg (Allais, Meier) |
| 그림문자(GHS): |
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| 신호 어: | Warning | ||||||||||||||||||||||||||||
| 유해·위험 문구: |
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| 예방조치문구: |
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1-GLYCERYL N-[7-CHLORO-4-QUINOLYL]ANTHRANILATE HYDROCHLORIDE C화학적 특성, 용도, 생산
용도
Glafenine is a non-narcotic analgesic agent. Glafenine shows significant antiinflammatory activity. Glafenine is widely used for the treatment of pains of various origins.정의
ChEBI: A carboxylic ester that is 2,3-dihydroxypropyl anthranilate in which the amino group is substituted by a 7-chloroquinolin-4-yl group. A non-steroidal anti-inflammatory drug, glafenine and its hydrochloride salt were used for the relief of all types of pain but high incidence of anaphylactic reactions resulted in their withdrawal from the market.World Health Organization (WHO)
Glafenine, a quinolylanthranilate derivative, was introduced in 1965 for use as an analgesic. By the late 1970s its use had been associated with severe allergic responses, including anaphylactoid reactions, which led to its withdrawal in one country whereas in others a warning to this effect is required in the product information. In 1992, on the advice of the Committee for Proprietary Medicinal Products of the European Communities, glafenine was eventually withdrawn worldwide by the major manufacturer.위험도
Moderately toxic by ingestion. Human systemic effects.1-GLYCERYL N-[7-CHLORO-4-QUINOLYL]ANTHRANILATE HYDROCHLORIDE 준비 용품 및 원자재
원자재
준비 용품
1-GLYCERYL N-[7-CHLORO-4-QUINOLYL]ANTHRANILATE HYDROCHLORIDE 공급 업체
글로벌( 67)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9348 | 55 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
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| Finetech Industry Limited | +86-27-87465837 +8618971612321 |
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| Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 |
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| Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | +8618829768577 |
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| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 |
sales@molcore.com | China | 49739 | 58 |
| Henan Allgreen Chemical Co.,LTD | +86-37155567971 +86-13633837469 |
info@allgreenchem.com | China | 5986 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 43348 | 58 |
| Aladdin Scientific | +1-833-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 |
jkinfo@jkchemical.com | China | 96815 | 76 |